意外早期胆囊癌的临床治疗与预后分析  

Clinical treatment and prognosis of early stage unexpected gallbladder carcinoma

作　　者：闫卫甫[1] 王金柱[1] 

机构地区：[1]漯河医学高等专科学校第二附属医院外一科,河南漯河462300

出　　处：《医药论坛杂志》2011年第13期36-37,共2页Journal of Medical Forum

摘　　要：目的分析意外发现的早期胆囊癌的临床治疗方法与预后。方法回顾性分析2005年5月至2010年5月漯河医学高等专科学校第二附属医院外一科收治的28例意外早期胆囊癌临床病理资料,对其治疗方法及影响预后的因素进行分析。结果 28例术中快速冰冻切片或术后病理切片证实为早期胆囊癌(NevinⅠ～Ⅱ期)。11例行单纯胆囊切除术,17例行根治术。多因素分析表明,组织学分级、Nevin分期及手术方式是影响预后的独立因素,单纯胆囊切除术组与胆囊癌根治术组患者的生存率差异有统计学意义。结论早期胆囊癌术前诊断困难,术中对可疑者做快速冰冻切片检查有助于发现早期胆囊癌,术中及术后一旦确诊即予施行根治术。Objective To explore the clinical treatment and prognosis of early stage unexpected gallbladder carcinoma.Methods The clinical and pathological data of 28 patients with early stage gallbladder carcinoma treated in our hospital from May 2005 to May 2010 were retrospectively summarized,in which different treatment and factors affecting prognosis were analyzed.Results All the 28 cases were confirmed as early stage gallbladder carcinoma（Nevin Ⅰ～Ⅱ stage） by frozen section examination during operation or pathological examination after operation.17 cases underwent radical resection,11 cases simple cholecystectomy.Multivariate analysis showed that histological differentiation,Nevin stage and surgical methods were the independent factors for prognosis of early stage unexpected gallbladder carcinoma.There was significant difference between patients who received radical resection and those who not.Conclusions It is difficult to diagnose the early stage gallbladder carcinoma before operation.Frozen section contributes to the early diagnosis of unexpected gallbladder carcinoma examination.Radical resection should be performed once the diagnosis is confirmed by pathological evidence,whenever during operation or after operation.

关 键 词：意外早期胆囊癌 临床治疗 预后 

分 类 号：R735.8[医药卫生—肿瘤]