乙醛酸法合成香兰素的研究  

Research on the synthesis of vanillin from glyoxylic acid

作　　者：周亚婷[1] 杨昌楠 刘宇[1] 姜丹蕾[1] 

机构地区：[1]中国石油吉林石化公司研究院,吉林吉林132021 [2]中国石油东北炼化工程有限公司吉林设计院,吉林吉林132005

出　　处：《化工科技》2011年第4期27-30,共4页Science & Technology in Chemical Industry

基　　金：中国石油天然气集团公司应用基础研究项目(06A50201)

摘　　要：对愈创木酚与乙醛酸缩合-氧化法制备香兰素工艺进行了研究,对缩合反应中的反应温度、反应液的pH值、加料方式、原料配比以及氧化反应中的催化剂、介质的pH值、反应时间、温度等反应条件进行了优化,使香兰素总收率达到75%,产品纯度>99%。该工艺国内领先,接近国际先进水平,为实现产业化奠定了基础。The preparation process of vanillin from guaiacol and glyoxylic aid was investigated.The condersation reaction conditions including reaction temperature,pH valve of reaction solution,raw material feeding way were optimized.The oxidation reaction conditions including catalyst,reaction time,temperature and so on were also optimized.Under these conditions the total yield of vanillin can reach 75%,purity of product is over 99%.This technology,has been close to the advanced level in the world and it has established the foundation for realizing industrialization.

关 键 词：香兰素 乙醛酸 愈创木酚 

分 类 号：TQ655[化学工程—精细化工]