植入式微电子神经信道桥接系统体内无线供电模块设计及实验  

Design and Experiment of Wireless Power Supply Module for in vivo Neural Bridging Chip

作　　者：李贵阳[1] 吕晓迎[1] 赵海涛[1] 龚鑫[1] 王志功[2] 

机构地区：[1]东南大学生物电子学国家重点实验室,南京210096 [2]东南大学射频与光电集成电路研究所,南京210096

出　　处：《中国生物医学工程学报》2011年第4期595-601,共7页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学基金(90307013;90707005;61076118);江苏省自然科学基金创新学者攀登项目(BK2008032)

摘　　要："植入式微电子神经桥芯片"是采用微电子的方法实现脊髓损伤功能恢复的植入式系统。为解决这一系统的供能问题,设计并制作了无线经皮能量传输系统的体内供电模块。该模块包括接收线圈、整流芯片和稳压芯片,其中接收线圈利用印刷电路板(PCB)实现,整流芯片和稳压芯片利用CMOS工艺实现。通过板上芯片封装(COB)技术,将各个部分组成体内供电模块。配合前期制作的发射模块,利用猪皮等动物组织,进行模拟植入情况的"包埋式"能量传输实验。实验结果表明,尽管动物组织对能量传输效率的影响较大,但体内供电模块仍然可以为后续芯片电路提供1.8 V的工作电压,初步实现了神经桥芯片的供能。＂Implantable microelectronics neural channel bridging SOC＂ has been proposed to recover the function of an injured spinal cord.This article utilizes a wireless transcutaneous energy transmission system to provide the power supply for an SOC.Such an in-vivo module includes one or two receiving coils,a rectifier,and a regulator.The receiving coils were prepared by printed circuit boards（PCB） and the rectifier and the regulator were fabricated by CMOS technique.The power supply module is assembled via the chip-on-board（COB） technique.Based on the animal tissue such as pig skin,＂embedded-style＂ energy transfer experiments were performed according to the practical implantation.The experimental results demonstrated that the circuits could still supply a voltage up to 1.8 V for the subsequent circuits and tentatively provide power supply of the SOC,although the animal tissue had a relatively severe influence on the energy transmission efficiency.

关 键 词：无线经皮供能 CMOS工艺 整流 低压差稳压 “包埋式”实验 

分 类 号：R318.08[医药卫生—生物医学工程]