异种脱细胞真皮基质在牙种植中引导骨再生的临床观察  

Exogenic Acellular Dermal Matrix in Guided Bone Regeneration of Dental Implant

作　　者：韦丽萍[1] 左陈启[1] 王远勤[1] 

机构地区：[1]暨南大学附属惠州口腔医院修复科,广东惠州516001

出　　处：《口腔颌面外科杂志》2011年第4期281-283,共3页Journal of Oral and Maxillofacial Surgery

摘　　要：目的:观察国产异种脱细胞真皮基质修复膜作为屏障膜,在牙种植的引导骨再生中应用的临床效果。方法:78例需要引导骨再生的种植病例,均为前牙区或前磨牙区单牙或连续多牙位(3牙)缺失;其中前牙52颗,前磨牙26颗。缺牙区牙槽嵴主要为唇颊侧垂直性吸收,牙槽嵴顶宽度约1～3 mm,牙槽嵴水平吸收量在2 mm以内。分为2组,一组采用国产异种脱细胞真皮基质修复膜作为GBR技术的屏蔽膜(38例),另一组采用Bio-Gide生物膜作为对照(40例),比较二者的临床效果。结果:2组在骨生长效果之间的差异无统计学意义(P>0.05)。2组患者切口均甲级愈合,切口愈合率均为100%。术后3 d,对照组有1例发生面部肿胀,经抗感染治疗和对症处理后缓解。本研究的其他病例均未出现感染等不良事件。结论:使用国产异种脱细胞真皮基质修复膜在牙种植术中进行骨引导再生,成本低廉,能达到促进种植体周围成骨的要求,与进口Bio-Gide生物膜的临床效果一样,值得推广。Objective： To identify the clinical effect of a homemade exogenic acelluar dermal matrix as a barrier membrane in guide bone regeneration （GBR） of dental implants. Methods： Seventy eight dental implants/eases with limited bone-bed were divided into 2 groups, and treated by GBR technology with different barrier membrane. Experiment group （38 cases） used homemade exogenic acelluar dermal matrix, while in the control group （40 cases） Bio-Gide biofilm was used. Results： The difference of bone harvested in two groups was not statistically significant （P〉0.05）. All patients were healed with first intention and the healing rate of 2 groups were all 100%. One case complicated with facial swelling in control group, which was cured after anti-inflammatory and symptomatic treatment. There was no statistically significant between two groups in the demographic basic information, such as, adverse events, healing of incision, bone growth effect, and the like. Conclusion： This alternative homemade material should be considered in GBR by practitioners.

关 键 词：脱细胞真皮基质修复膜 屏障膜 引导骨再生 牙种植 

分 类 号：R782.1[医药卫生—口腔医学]