原发性肠道T细胞淋巴瘤临床特点分析  

作　　者：钟伟杰[1] 

机构地区：[1]广东省广州市第一人民医院老年病科血液肿瘤病区

出　　处：《当代医学》2011年第26期100-101,共2页Contemporary Medicine

摘　　要：目的通过病例分析了解原发性肠道T细胞淋巴瘤临床特点。方法回顾分析收治的5例原发性肠道T细胞淋巴瘤患者的临床资料。结果本组5例患者,男性2例,女性3例,中位年龄51.6岁。病变多位于回肠或回盲部。临床表现以腹痛、体重下降、发热、腹泻为主。免疫表型CD3、CD45RO、TIA-1、粒酶B阳性,CD20、CD79α、CK阴性。生存时间2周～12个月,中位生存期2个月,5例均于确诊1年内死亡。结论原发性肠道T细胞淋巴瘤临床上极为少见,临床表现缺乏特异性,病程凶险,目前无有效治疗方案,预后差。Objective To learn the clinical characteristics of primary intestina T-cell lymphoma by case analysis.Methods All 5 cases of ITCL admitted in Guangzhou First Municipal People＇s Hospital were collected and analyzed retrospectively.Results The 5 patients include 3 females and 2 males,the median age is 51.6.The tumor mainly occurred in the ileum or ileocecal.The main clinical manifestations were abdominal pain,weight loss,fever, diarrhea.The immunophenotype were CD3. CD45RO. TIA- 1. Granzyme B positive, CD20. CD79a. CK negative.The survival time was from 2 weeks to 12 months,the median survival time was 2 months,5 patients all died within 1 year after diagnosis.Conclusion PITCL is clinical rare,dangerous,the clinical manifestations are not specific.The disease now has no effective treatment and has a poor prognosis.

关 键 词：肠肿瘤 淋巴瘤 T细胞 免疫表型 

分 类 号：R735.3[医药卫生—肿瘤]