高龄老人血清白蛋白和血清前白蛋白水平分析  

Analyzing the levels of serum albumin and prealbumin in the 59 cases of nonagenarians

作　　者：赵擎[1] 蔡昌豪[1] 王刚石[1] 吴本俨[1] 

机构地区：[1]解放军总医院南楼临床部消化科,北京100853

出　　处：《中华保健医学杂志》2011年第4期292-294,共3页Chinese Journal of Health Care and Medicine

摘　　要：目的观察高龄老人血清白蛋白、血清前白蛋白水平与疾病的关系。方法≥90岁高龄老人59例,根据所患疾病分为带瘤组(16例)、感染组(26例)和慢性病组(17例)3组,检测血清白蛋白、前白蛋白水平。结果带瘤组血清白蛋白水平[(32.38±3.42)g/L]低于感染组[(35.42±4.51)g/L]和慢性病组[(36.85±4.11)g/L],带瘤组血清前白蛋白水平[(12.88±3.72)g/L]低于感染组[(22.12±4.78)g/L]和慢性病组[(22.79±3.67)g/L],差异均有统计学意义(P<0.01)。结论高龄老人分解代谢增强,合成代谢减弱,容易发生负氮平衡;肿瘤的长期慢性消耗、营养摄入不足导致血清白蛋白和血清前白蛋白水平降低。Objective To study the levels of serum albumin and prealbumin in nonagenarians,and to analyze the relationship with the comorbid diseases. Methods According to the comorbid diseases,59 patients were divided into 3 groups： the group of having tumors,the group of having inflammation,and the group of having chronic diseases. The levels of serum albumin and prealbumin in these patients were detected. Results The levels of serum albumin in the group of having tumors （32.38±3.42）g/L,d creased compared to the group of having inflammation （35.42±4.51）g/L,and the group of having chronic diseases （36.85±4.11）g/L,had statistically difference（P〈0.01 ）. The levels of serum prealbumin in the group of having tumors（12.88±3.72）g/L,decreased significantly compared to the group of having inflammation （22.12±4.78）g/L, and the group of having chronic diseases （22.79±3.67）g/L, had statistically difference （P〈0.01）. Conclusions In the aged ,the catabolism increased ,the anabolism decreased ,which can induce negative nitrogen balance easily. The tumor cause chronic exhaustion and malnutrition of the body ,which lead to the decreasing of the levels of serum albumin and prealbumin.

关 键 词：血清白蛋白 血清前白蛋白 肿瘤 感染 慢性疾病 高龄 

分 类 号：R73[医药卫生—肿瘤]