马来酸曲美布丁联合匹维溴胺治疗肠易激综合征的疗效观察  

Study on the Efficacy of Trimebutine Maleate Combined with Pinaverium bromide in Treatment of Irritable Bowel Syndrome

作　　者：刘修莉[1,2] 李玲[1,2] 任习芳[1,2] 潘群[1,2] 龚发良[1,2] 

机构地区：[1]三峡大学人民医院 [2]宜昌市第一人民医院,宜昌443000

出　　处：《临床消化病杂志》2011年第4期210-211,共2页Chinese Journal of Clinical Gastroenterology

摘　　要：目的观察马来酸曲美布丁联合匹维溴胺治疗肠易激综合征的疗效。方法将100例肠易激综合征患者随机分为2组:实验组(57例)应用马来酸曲美布丁0.1g tid、匹维溴胺50 mg tid治疗;对照组(43例)应用匹维溴胺50 mg tid治疗,疗程均为4周。结果实验组总有效率88%,对照组总有效率74%,存在显著性差异。结论马来酸曲美布丁联合匹维溴胺治疗肠易激综合征的疗效更好。Objective Study on the efficacy of trimebutine maleate combined with pinaverium bromide in treatment of irritable bowel syndromec（IBS）.Methods 100 IBS patients were randomly divided into two groups.57 patients in treatment group received trinebutine maleate 0.1g tid and pinaverium bromide 50 mg tid.43 patients in control group only received pinaverium bromide 50 mg tid.The period of the treatment is 4 weeks.Result The effect for the treatment group is 88% and the effect for the control group is 74%（P0.05）.Conclusion Trimebutine maleate combined with pinaverium bromide is a more effective treatment for IBS.

关 键 词：肠易激综合征 马来酸曲美布丁 匹维溴膦 

分 类 号：R574.4[医药卫生—消化系统]