氪黄激光光凝联合球后注射曲安奈德治疗糖尿病性黄斑水肿  

Macular Photocoagulation by Krypton Yellow Laser Combined with Retrobulbar Injection of Triamcinolone Acetonide for Diabetic Macular Edema

作　　者：彭志华 陈中山[2] 金小琴 吴岚 宋艳萍[2] 

机构地区：[1]武汉艾格眼科医院,武汉市430070 [2]广州军区武汉总医院全军眼科中心

出　　处：《中国激光医学杂志》2011年第4期221-225,共5页Chinese Journal of Laser Medicine & Surgery

摘　　要：目的探讨氪黄激光黄斑格栅光凝联合球后注射曲安奈德(TA)治疗糖尿病性黄斑水肿的方法及疗效。方法对123例215只眼糖尿病性黄斑水肿患者进行黄斑部氪黄激光格栅光凝联合球后注射TA治疗,同时选择同期采用其他药物治疗的糖尿病性黄斑水肿患者79例144只眼作为对照组。治疗前后行视力、眼压、眼底,以及眼底荧光造影(FFA)和光学相干层析(OCT)检查。随访1年,观察治疗前后患者视力、黄斑水肿和黄斑区视网膜厚度的变化。结果光凝联合TA组治疗后患者视力提高者112只眼(52.1%),黄斑水肿完全消退者137只眼(63.7%),部分消退者69只眼(32.1%),黄斑区视网膜厚度正常者122只眼(56.7%);对照组治疗后视力无提高,黄斑水肿无完全消退者,部分消退者2只眼(1.4%),黄斑区视网膜厚度无达正常者。两组比较,差异具有非常显著意义。结论氪黄激光光凝联合球后注射TA治疗糖尿病性黄斑水肿疗效显著,无明显并发症发生。Objective To explore the clinic therapeutic methods and effect of macular grid photocoagulation by krypton yellow laser combined with retrobulbar injection of triamcinolone acetonide（TA） for diabetic macular edema,and to investigate the safety of treatment. Methods Totally 123 patients（215 eyes） diagnosed as diabetic macular edema were performed with macular grid photocoagulation by krypton yellow laser combined with retrobulbar injection of TA（combined group）.The control group of 79 patients（144 eyes） was treated with other drugs.The best-corrected visual acuity（BCVA）,examination of the ocular fundus,FFA and OCT were investigated before and after treatment. Results At the final follow-up,in combined group,BCVA improved in 112 eyes（52.1%）,complete resolution of macular edema in 137 eyes（63.7%）,partial resolution in 69 eyes（32.1%）,and macular retinal thickness became normal in 122 eyes（56.7%）.In control group,no one improved their BCVA and experienced complete resolution of macular edema,partial resolution was in 2 eyes（1.4%）,and no one had normal macular retinal thickness.The difference between combined and control groups was significant. Conclusions Macular grid photocoagulation by krypton yellow laser combined with retrobulbar injection of TA is effective for the patients with diabetic macular edema,and no obvious complications occurred.

关 键 词：激光 糖尿病 黄斑水肿 

分 类 号：R774.5[医药卫生—眼科]