超声引导经皮无水乙醇注射治疗肝癌伴发门静脉癌栓  

Ultrasound-guided percutaneous ethanol injection in the treatment of hepatocellular carcinoma combined with portal vein tumor thrombosis

作　　者：张秀娟[1] 林礼务[1] 薛恩生[1] 陈志奎[1] 俞丽云[1] 

机构地区：[1]福建医科大学附属协和医院超声科福建省超声医学研究所,福建福州350001

出　　处：《中国介入影像与治疗学》2011年第5期367-370,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：福建省科技厅重点资助项目(2000Z138)

摘　　要：目的评价超声引导经皮无水乙醇注射（PEI）治疗肝细胞癌（HCC）伴发不同类型门静脉癌栓（PVTT）的临床应用价值。方法对90例HCC伴不同类型PVTT患者行超声引导PEI治疗,每周1-2次。治疗结束后随访12-60个月,统计患者1-5年生存率。结果 90例患者治疗后1-5年生存率分别为52.22%、23.33%、15.56%、12.22%、10.00%,中位生存时间为12个月。不同类型PVTT患者生存率不同,分型越低者生存时间越长。结论超声引导PEI治疗HCC伴发PVTT安全、有效,可明显延长分型较低癌栓患者的生存时间。Objective To assess the clinical value of ultrasound-guided percutaneous ethanol injection（PEI） in the treatment of hepatocellular carcinoma（HCC） combined with portal vein tumor thrombosis（PVTT）.Methods Ninety HCC patients with different type PVTT underwent ultrasound-guided PEI once or twice a week.The follow-up lasted 12 to 60 months,and the 1-,2-,3-,4-and 5-year survival rates were calculated.Results The median survival time of HCC combined with PVTT patients treated with PEI was 12 months,and the 1-,2-,3-,4-and 5-year survival rates was 52.22%,23.33%,15.56%,12.22% and 10.00%,respectively.The survival rate correlated significantly to the type of PVTT.The lower the type of PVTT was,the longer the patients lived.Conclusion Ultrasound-guided PEI is a safe and effective method for the treatment of HCC combined with PVTT,and can prolong the survival time of HCC patients with low type PVTT.

关 键 词：癌 肝细胞 门静脉 静脉癌栓 超声检查 介入性 无水乙醇 

分 类 号：R735.7[医药卫生—肿瘤]