由三态跃迁机制产生的两种神经放电节律  

Two Types of Neural Firing Rhythms Generated by Transitions between Three States

作　　者：崔睿[1] 王姗姗[1] 李晋[1] 王栋[1] 刘一辉[1] 任维[1] 

机构地区：[1]陕西师范大学生命科学学院

出　　处：《生物物理学报》2011年第8期703-711,共9页Acta Biophysica Sinica

基　　金：国家自然科学基金青年项目(30900443)~~

摘　　要：在实验性神经起步点自发放电中,发现了两种三态跃迁节律,其特征为静息、周期n及周期n+1(n=1,2)簇放电随机交替出现。应用随机Chay模型数值仿真,分别得到了与实验模型中相似的两种三态跃迁节律,这两种节律都是在两个紧邻的分岔点附近,由噪声驱动而产生的。理论分析提示,当神经元系统接近从静息经分岔到放电的临界状态,且从静息到周期n的分岔点,与从周期n到周期n+1的分岔点非常接近时,在噪声的作用下,系统运动会在静息、周期n和周期n+1三种状态之间随机跃迁,从而形成了这种三态跃迁节律。基于这种三态跃迁放电的随机共振,还有待进一步深入研究。Two types of neural firing rhythms composed of three patterns were observed in an experimental neural pacemaker model.The behavior of such rhythms were dynamic transitions among quiescence,period n burst and period n＋1 burst（n =1,2）.The stochastic Chay model could simulate these two types of firing rhythms.These firing rhythms were induced near two closed period adding bifurcation points in presence of noise.These firing rhythms were generated by noise-induced dynamic transition between three states separated by two bifurcation points that were quite near.

关 键 词：动态跃迁 随机Chay模型 分岔 神经放电 

分 类 号：Q424[生物学—神经生物学]