中晚期直肠癌术前同步放化疗近期疗效观察  

Observation on short-term efficacy of preoperative chemo-radiotherapy for intermediate and advanced stage carcinoma of rectum

作　　者：李小武[1] 范立[1] 韩晓栋[1] 

机构地区：[1]山西省肿瘤医院放疗五病区,太原030013

出　　处：《山西医科大学学报》2011年第8期685-688,共4页Journal of Shanxi Medical University

摘　　要：目的中晚期直肠癌实行术前同步放化疗较术前单纯放疗有无优越性。方法选取我院就诊的中晚期直肠癌患者65例,其中34例患者采取术前同步放化疗,余31例患者行单纯术前放疗,对比两组生存率、手术保肛率、放化疗急性反应发生率及严重程度。结果与术前放疗组比较,术前同步放化疗组可明显提高患者近期有效率(P<0.05),但第1年、第3年总生存率和术中保肛率差异无统计学意义。结论术前同步放化疗较术前单纯放疗能更好地提高近期有效率。Objective To explore the advantages of preoperative chemo-radiotherapy for intermediate and advanced stage carcinoma of rectum.Methods Sixty-five patients with intermediate and advanced stage carcinoma of rectum cancer were divided into two groups：chemo-radiotherapy group（n=34） and radiotherapy group（n=31）.The survival rate,the sphincter-saving rate in operation,incidence and degree of acute side reaction of chemo-radiotherapy were compared between 2 groups.Results Compared with radiotherapy group,the short-term efficacy in chemo-radiotherapy group significantly increased（P0.05）,but there was no significant difference in 1,3-year survival rates and sphincter-saving rate in operation between two groups.Conclusion Chemo-radiotherapy is better in short-term efficacy for preoperative carcinoma of rectum than radiotherapy.

关 键 词：放化疗 直肠癌 单纯放疗 

分 类 号：R735.37[医药卫生—肿瘤]