肝豆状核变性病患者血清微量元素含量分析  

Analysis and Discussion on Trace Elements in serum from Patients with Hepatolenticular Degeneration disease

作　　者：陈红英[1] 林广云[2] 许燕春[3] 林爱华[4] 张丹桃[5] 郑民樱[5] 林芳宇[5] 邓石凤[5] 

机构地区：[1]中山大学珠海校区基础教学实验中心,珠海519082 [2]中山大学医学教学实验中心,广州510080 [3]广州医学院附属第一医院,广州510000 [4]中山大学卫生学院 [5]中山大学附属第一医院,广州510080

出　　处：《微量元素与健康研究》2011年第5期11-12,共2页Studies of Trace Elements and Health

摘　　要：目的:探讨肝豆状核变性病与微量元素的关系。方法:采用火焰原子吸收分光光度法测定肝豆状核变性病患者血清铜、锌、铁、钙、镁含量。结果:肝豆状核变性病患者组与对照组的血清铜、血清钙含量比较明显低下(P<0.05),有显著性差异。血清锌、铁、镁含量两组间差异无统计学差异。结论:血清铜测定能作为肝豆状核变性病的诊断指标,血清钙测定对肝豆状核变性病治疗有一定的辅助作用。Objective： to reveal the relationhship of hepatolenticular degeneration disease with certain trace elements. Medthods： emplo- ying the method of the Flame Atomic Absorption Spectrophoto - meter to assess the content of Cu, Zn, Ca,Fe in serum from the patients with hepatolenticular degeneration disease. Rusults ： Compared to the control group, the serum Cu and Ca from the hepatolenticular de- generation disease group are obviously lower,which is significant in statistic（P 〈0. 05 ）. Whereas, no significance for Zn, Fe and Mg between these two groups. Conlusions： Serum Cu detection can be used as an index for diagnosis of hepatolenticular hegeneration dis- ease, and analysis of serum Ca may bear value for guidance in therapy of hepatolenticular degeneration disease.

关 键 词：肝豆状核变性病 血清 微量元素 

分 类 号：Q592.1[生物学—生物化学]