黑龙江地区口腔扁平苔藓患者丙型肝炎病毒感染的检测  

Detection of Hepatites C virus infection among patients with oral lichen planus in Heilongjiang area

作　　者：张成仁[1] 靳慧[1] 葛娅娜[1] 王秀梅[1] 张梅兮[1] 

机构地区：[1]哈尔滨医科大学附属二院口腔科,哈尔滨150086

出　　处：《口腔医学》2011年第8期485-487,共3页Stomatology

基　　金：黑龙江省自然科学基金资助项目(D2007-01);黑龙江省博士后科研启动基金(LRB05-279)

摘　　要：目的检测黑龙江地区口腔扁平苔藓(OLP)患者丙型肝炎病毒(HCV)的感染率,并讨论两者之间的关系。方法采用双抗夹心酶联免疫吸附试验(ELISA)对本地区62例OLP患者和61例非OLP黏膜病患者及22例健康志愿者进行血清丙型肝炎病毒抗体(HCV-Ab)的检测。结果口腔扁平苔藓组HCV感染率(9.7%)明显高于非OLP黏膜病组(1.6%)和健康组(0%)HCV感染率(P<0.05)。结论黑龙江地区OLP的发病与HCV感染存在一定的关系。Objective To detect the prevalence of Hepatites C Virus（HCV）infection among patients with oral lichen planus（OLP）in Heilongjiang area,and to assess the association between OLP and HCV infection.Methods 62 OLP patients and 61 patients with other oral mucosa disease（non-OLP patients）were recruited into the study,and 22 healthy volunteers were used for controll study.Serum anti-HCV antibodies were measured by enzyme-linked immunosorbent assay（ELISA）.Results The prevalence of HCV infection was significantly higher in OLP patients（9.7%）in comparison to non-OLP patients（1.6 %）and healthy subjects（0%）（P0.05）.Conclusions The result suggests that,in Heilongjiang area,there is association between OLP and HCV infection.

关 键 词：口腔扁平苔癣 丙型肝炎病毒 感染 筛查 

分 类 号：R781.5[医药卫生—口腔医学]