外伤性蛛网膜下腔出血患者血清镁离子及神经元特异性烯醇化酶的动态监测意义  

Clinical study of serum Mg～(2+) and NSE levels in patients with traumatic subarachnoid hemorrhage

作　　者：史建国[1] 董亚南[1] 高军[1] 杜斌[1] 彭洪海[1] 孟雷[1] 

机构地区：[1]山东大学附属济南市中心医院神经外科,山东济南250013

出　　处：《中国医药科学》2011年第17期55-56,共2页China Medicine And Pharmacy

摘　　要：目的观察外伤性蛛网膜下腔出血患者血清Mg2+及NSE水平的变化。方法络合指示剂法和免疫抑制法检测50例外伤性蛛网膜下腔出血患者发病24h内、第3、7天血清Mg2+及NSE浓度水平并与对照组比较。结果外伤性蛛网膜下腔出血患者外周血中Mg2+及NSE浓度与对照组比较差异有统计学意义(P<0.05)。结论 Mg2+及NSE参与外伤性蛛网膜下腔出血的病理生理过程,其测定对于早期评估其严重程度有重要的临床参考意义。Objective To study dynamically the serum Mg2＋ and NSE levels in patients with traumatic subarachnoid hemorrhage.Methods To measure the serum NSE levels at l,3,7d after onset of tSAH in 50 patients（Mg2＋-complexometric indicator method,NSEgreen method）.Results The serum Mg2＋ and NSE levels in patients with tSAH were higher than the normal controls（P0.05）.Conclusion Mg2＋ and NSE were involved in the pathological process of traumatic subarachnoid hemorrhage.Determination of their plasma contents were of clinical importance for evolution of the severity of injury.

关 键 词：蛛网膜下腔出血 镁离子 神经元特异性烯醇化酶 

分 类 号：R743.35[医药卫生—神经病学与精神病学]