靶向治疗晚期结直肠癌新进展  

Progress on Tartgeted Therapy for Advanced Colorectal Cancer

作　　者：唐焱[1] 高丽霞[1] 

机构地区：[1]新疆克拉玛依市中心医院血液肿瘤科,新疆克拉玛依834000

出　　处：《医学综述》2011年第17期2620-2622,共3页Medical Recapitulate

摘　　要：结直肠癌是消化道常见的恶性肿瘤之一,其治疗方法主要以手术切除为主,辅助进行化疗和放疗,但是这些治疗方法都不能达到满意的疗效。近年来分子靶向治疗逐渐成为研究热点。有关表皮生长因子受体和血管内皮因子受体等与结直肠癌的发生、发展和转移的关系及其信号传导机制的研究也有了很大进展。因此,分子靶向药物导向治疗有望成为治疗结直肠癌的有效手段。Colorectal cancer is one of common malignant tumors in the digestive tract, and the patient was treated with surgery and adjuvant chemotherapy and radiotherapy, but these treatments fail to achieve satisfactory results. In recent years,molecular targeted therapy has become a hot spot. Great progress has been made in the research that described the relation between epidermal growth factor, vascular endothelial growth factor receptors and the occurrence, development and transfer of colorectal cancer, its signal transmission mechanism. Therefore,the molecular targeted drug and treatment of eolorectal cancer is expected to become an effective means of treatment.

关 键 词：结直肠癌 单克隆抗体 西妥昔单抗 

分 类 号：R735.34[医药卫生—肿瘤]