射频消融与无水乙醇注射治疗原发性小肝癌的临床疗效分析  

Clinical effect of radiofrequency ablation therapy and percutaneous ethanol injection therapy on small hepatocellular carcinoma

作　　者：王学文[1] 杨森[1] 赖钊[1] 何晓非[1] 

机构地区：[1]自贡市第四人民医院肝胆外科,四川自贡643000

出　　处：《西部医学》2011年第9期1671-1673,共3页Medical Journal of West China

摘　　要：目的探讨射频消融与无水乙醇注射治疗原发性小肝癌患者的临床疗效。方法对98例原发性小肝癌患者(SHCC)进行射频消融(RFA)及经皮瘤体内无水乙醇注射治疗(PEIT)。98例病人随机分为RFA组49例共60个病灶,PEIT组(对照组)49例共76个病灶。比较患者RFA及PElT治疗后的近期疗效(肿瘤消融率),第1、2年生存率和术后并发症。结果两组患者术后均无严重并发症;肿瘤消融率RFA组为93.8%;PEIT为组77.5%;RFA组肿瘤消融率高于PEIT组(P<0.05)。RFA组术后1、2年生存率分别为95.9%9、1.8%;PEIT组病术后1、2年生存率分别为85.7%7、7.5%;RFA组1,2年生存率高于PRIT组(P<0.05)。结论对于SHCC的治疗,RFA临床疗效优于PEIT;但位于肝脏表面、靠近第一,二,三肝门的SHCC,以PEIT较为安全。Objective To study clinical effect radiofrequency ablation（RFA） and percutaneous ethanol injection therapy（PEIT） on small hepatocellular carcinoma（SHCC）.Methods 98 patients of primary small hepatocellular carcinoma（SHCC） were treated with radiofrequency ablation（RFA） or percutaneous intratumoral ethanol injection therapy（PEIT）.The tumor ablation rate,survival rate,postoperative complications between RFA and PEIT in the first two years were observed.Results There were no serious complications in the two groups.The tumor ablation rate of PEIT group was 77.5%,while the tumor ablation rate of RFA was 93.8%.The tumor ablation rate of RFA wass higher than that of PEIT group（P〈0.05）.1-year survival of RFA group was 95.9%,while 1-year survival of PEIT group was 85.7%;2-year survival of RFA group was 91.8% while 1-year survival of PEIT group was 77.5%.1,2-year survival rate of RFA group was higher than that of PRIT group（P〈0.05）.Conclusion For the treatment of SHCC,RFA is better than PEIT in the clinical effect;PEIT is more secure in SHCC locating in surface of the liver or close to one,two and three hilar.

关 键 词：小肝癌 射频消融 乙醇注射 临床疗效 

分 类 号：R735.7[医药卫生—肿瘤]