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机构地区:[1]佛山市南海区第二人民医院,广东佛山528251 [2]南方医科大学附属口腔医院 [3]广东省口腔医院,广东广州510280
出 处:《热带医学杂志》2011年第8期917-919,930,共4页Journal of Tropical Medicine
摘 要:目的评估一组中重度牙周炎伴Ⅱ型糖尿病患者牙周基础治疗对牙周临床指标的影响,以及代谢控制、患病时间对近期疗效的影响。方法选取60名中重度牙周炎伴Ⅱ型糖尿病患者为实验组,以48名无系统性疾病的中重度牙周病患者为对照组,两组患者均行牙周基础治疗和药物治疗,分别记录并比较两组患者治疗前后的各项牙周临床指标,包括探诊深度(PPD)、探诊出血指数(BOP)、附着丧失(CAL)。结果实验组和对照组的BOP治疗前与治疗后3个月、6个月比较,均有明显改善(P<0.05),两组患者的PPD和CAL治疗后均有改善,但差异无统计学意义;两组患者治疗后3个月与6个月的各项临床指标没有明显改变;实验期间两组患者的各项牙周临床指标的变化,差异无统计学意义。治疗前后的变化:BOP与CAL在罹患糖尿病病史长短不同的两组中差异有统计学意义(P<0.05),BOP以及PPD在血糖控制差与血糖控制良好的两组中差异有统计学意义。结论糖尿病并牙周炎的牙周基础治疗是有效的,且疗效稳定,不需激进的治疗方式。血糖控制不良、糖尿病病史较长的糖尿病并牙周炎患者的疗效比血糖控制良好、糖尿病病史短的患者差。Objective To evaluate the effect of the periodontal therapy on type-2 diabetes and moderate to severe chronic periodontitis patients and the effect of metabolic control of patients after controlling periodontal disease.Methods A total of 60 male and female patients with type-2 diabetes and moderate to severe chronic periodontitis were treated with periodontal therapy.Control group,consisting of 48 moderate to severe chronic periodontitis patients with non-system disease,received the same periodontal treatment.Periodontal parameters including pocket probing depth (PPD),bleeding on probing (BOP) and clinical attachment loss (CAL) were measured before and after the treatment.Results 3 to 6 months after therapy,the two groups had a statistically significant reduction on BOP (P0.05).The improvement on PPD,CAL and glycated hemoglobin (HbA1c) level in the two groups was minimal.All clinical variables and HbA1c level were detected with no statistical significance in these two groups.For BOP and CAL,a significant difference was observed in patients with deferent type-2 diabetes medical history(P0.05).Type-2 diabetes with moderate to severe chronic periodontitis and deficient metabolic control were associated with higher BOP and deeper PPD.Conclusion The baseline periodontal therapy is effective in maintaining periodontal health of chronic periodontitis patients with or without type-2 diabetes.No progressive treatment should be used to chronic periodontitis patients with type-2 diabetes.This method has a lower efficacy for type-2 diabetes and moderate to severe chronic periodontitis patients who have a poor controlled HbA1c level and longer medical history of type-2 diabetes.
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