足月窒息新生儿血乳酸测定及临床意义  

Detection and significance of blood lactate in term newborn with asphyxia

作　　者：韩素鸽[1] 

机构地区：[1]郑州市妇幼保健院新生儿科,郑州450012

出　　处：《医药论坛杂志》2011年第16期74-75,78,共3页Journal of Medical Forum

摘　　要：目的探讨窒息新生儿血乳酸水平与临床预后的关系。方法采用GEM Premier 3000分析仪对133例足月窒息新生儿生后1、9h动脉血乳酸水平进行测定,观察其与新生儿神经行为评分(NBNA评分)及其不良预后的关系。结果正常对照组、轻度窒息组与重度窒息组新生儿在生后1h的血乳酸水平为(3.56±0.8)mmol/L、(8.32±4.6)mmol/L和(12.13±4.4)mmol/L,P<0..01,在生后9h为(1.52±0.5)mmol/L、(3.4±1.0)mmol/L和(6.3±1.8)mmol/L,P<0.05;在生后2周的NBNA评分为(37.9±2.1)、(33.0±4.3)和(27.4±3.2),P<0.01,在生后3周为(38.3±1.5)、(37.2±1.6)和(33.1±2.7),P<0.01。结论窒息越严重,血乳酸水平越高,NBNA评分越低,不良预后越多。Objective To investigate the relationship between blood lactate and prognosis in term with asphyxia.Methods Blood samples from 133 term newborn with asphyxia were detected by using the Premier 3000 in different time first hour and ninth hour,and evalue the relation between blood lactate level and NBNA score.Results In first hour,the mild ones is（8.32±4.6）mmol/L,the severe ones is（12.13±4.4）mmol/L,P〈0.01.In ninth hour,the mild ones is（3.4±1.0）mmol/L,the severe ones is（6.3±1.8）mmol/L,P〈0.05.For NBNA sore,in second week postborn,the mild is（33.0±4.3）,the severe is（27.4±3.2）,P〈0.01.In third week postborn,the mild is（37.2±1.6）,the severe is（33.1±2.7）,P〈0.01.Conclusions The severe of asphyxia,the higher of blood lactate,the lower of NBNA score,the worse of prognosis.

关 键 词：窒息 月新生儿 乳酸 NBNA评分 

分 类 号：R446.1[医药卫生—诊断学]