抗菌淀粉-聚乙烯醇水凝胶的制备及性能  

Preparation and Properties of Antimicrobial Starch-PVA Hydrogel

作　　者：方媛[1] 朱琳琳[1] 危大福[1] 郑安呐[1] 胡福增[1] 管涌[1] 

机构地区：[1]华东理工大学材料科学与工程学院,上海市先进聚合物材料重点实验室,超细材料制备与应用教育部重点实验室,上海200237

出　　处：《功能高分子学报》2011年第3期280-287,共8页Journal of Functional Polymers

基　　金：教育部留学归国人员科研启动基金资助项目;国家自然科学基金项目(50573020)

摘　　要：以环氧氯丙烷为键合剂将胍盐低聚物(PHMG)接枝到淀粉分子上,设计了正交试验优化接枝反应条件。将产物添加到淀粉和聚乙烯醇(PVA)水溶液中,采用化学交联法合成了具有抗菌性能的淀粉-聚乙烯醇(S-PVA)水凝胶,测试了水凝胶的溶胀率、脱水率以及抗菌性能。结果表明:当反应温度为40°C、时间为0.5 h、pH为9时,PHMG的接枝效率最高,水凝胶的溶胀率随着PVA含量的增大而减小,随着交联剂用量的增加呈现先增大后减小的趋势。S-PVA水凝胶对大肠杆菌和金黄色葡萄球菌均显示出了优异的抗菌活性,当w(PHMG)=0.2%时,抑菌率达到100%。Starch grafted oligoguanidine（S-PHMG） was synthesized using epichlorohydrin as the bonding agent.Orthogonal tests were applied to optimize the reaction conditions.Antimicrobial starch-PVA hydrogels were synthesized from chemical crosslinked of starch,PVA and S-PHMG.The reswelling rate,dewatering rate and antimicrobial activity were determined.Results showed that the grafting efficiency could reach 22.15% at the optimal conditions： temperature 40 °C,time 0.5 h,pH=9.The reswelling rates of the hydrogels decreased with the increasing of PVA content,while increased at first and then decreased with the increasing of the crosslinker contents.S-PVA hydrogels exhibited high antimicrobial activities against both E.coli and S.aureus.When w（PHMG）=0.2%,the growth inhibition reached 100%.

关 键 词：水凝胶 淀粉 聚乙烯醇 胍盐低聚物 抗菌活性 

分 类 号：O63[理学—高分子化学] O648.17[理学—化学]