口服补液盐治疗成人急性感染性腹泻脱水的效果分析  

Effect of Oral Rehydration Salts in Adult Patients with Acute Infectious Diarrhea Dehydration

作　　者：姜天俊[1,2] 张秀[1,2] 范荣[1,2] 谢杨新[1,2] 赵鹏[1,2] 张昕[1,2] 李建静[1,2] 聂为民[1,2] 赵敏[1,2] 

机构地区：[1]中国人民解放军军医进修学院 [2]中国人民解放军第三0二医院感染一科,北京市100039

出　　处：《临床合理用药杂志》2011年第05X期101-103,共3页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨口服补液盐(ORS)治疗成人急性腹泻患者补液治疗的临床效果。方法 136例成人急性腹泻患者被纳入研究,69例随机分入口服补液治疗组(ORT组),临床评估为轻、中度脱水的患者采用ORS治疗,重度脱水患者早期采取静脉和ORS联合治疗,恢复至轻中度脱水后仅服用ORS。67例随机进入静脉输液组(IVT组),采用静脉补液治疗脱水。补液以外的其他治疗两组相似。比较两组患者的临床转归。结果 ORT组和IVT组在临床脱水纠正率、腹泻好转时间、不同时间电解质和酸碱紊乱恢复率间差异无统计学意义(P>0.05)。结论 ORS治疗成人急性腹泻脱水患者安全有效、简便易行,能在很大程度上减少静脉输液使用率。Objective To evaluate the effects on fluid infusion with oral rehydration salt （ORS） in adult acute infectious diarrhea patients. Methods A total of 136 patients were included in the study, 69 of whom received ORS treatment as observation group and another 67 of whom received intravenous transfusion treatment as control group, randomly. Severe dehydrated patients in observation group were treated with ORS and intravenous transfusion in the early stage, and then ORS only. Other therapeutic measures were similar in the two groups. Clinical effects of two different groups were compared. Results There were no significant difference between treatment groups in recovery time of dehydration, diarrhea, electrolyte disturbances and acid base disorder （P 〉 0. 05）. Conclusion These results suggest that ORS is safe and effective in treating adult acute infectious diarrhea patients, which can reduce the usage of venous transfusion remarkably.

关 键 词：补液疗法 脱水 腹泻 

分 类 号：R574.62[医药卫生—消化系统]