威利坦缓释片在孕妇急性贝尔面瘫中的应用  

Venostan for Bell's palsy in pregnant patients

作　　者：李健东[1] 刘永亮[1] 

机构地区：[1]北京世纪坛医院面神经研究室,北京100038

出　　处：《中华耳科学杂志》2011年第2期203-205,共3页Chinese Journal of Otology

摘　　要：目的孕妇面瘫是临床棘手的难题,由于患者处于特殊生理阶段,用药选择时需考虑胎儿的安全。本研究的目的旨在寻找一个能在孕期使用的有效治疗面瘫的药物。方法对2007年3月至2010年6月我院接诊的孕妇急性贝尔面瘫患者,给予威利坦缓释片每次800mg、每日2次口服治疗,能坚持服药10天者共计21人,治疗前后用Sunnybrook评分系统进行评分,对疗效和不良反应进行记录和统计分析。结果本组威利坦缓释片面瘫治愈率达76.2%,另有5人疗效较差,仅有1例出现胃肠道不良反应。结论孕妇急性贝尔面瘫患者使用威利坦缓释片治疗10天是安全有效的,可以作为一种新的保守治疗方法。Objective Facial paralysis in pregnant women is a difficult clinical problem. The purpose of this investigation was to find a safe and effective medicine for acute Bell＇s Palsy in pregnancy. Methods From March 2007 to June 2010,21 pregnant women with acute Bell＇s palsy were treated with Vesoatan sustained-release tablets （800 rag, po, bid, 10 days）. Sunnybrook Facial Grading System was used to evaluate facial function before and after treatment, and adverse reactions were recorded and analyzed. Results After 10 days of treatment, the Sunnybrook score was over 60 in 14 pa- tients , 55 in 1 patient and 44 in 1 patient. These 16 patients （76.2%） showed complete recovery at follow ups. The re- maining 5 patients had poor outcomes and one of them underwent a facial nerve decompression surgery. One patient expe- rienced gastrointestinal adverse reactions which were alleviated by taking the medicine with meals. Conclusion Vesoatan sustained-release tablet appears safe and effective for acute Bell＇s palsy in pregnancy.

关 键 词：妊娠 面神经麻痹 BELL面瘫 威利坦 激素 

分 类 号：R745.12[医药卫生—神经病学与精神病学] R453[医药卫生—临床医学]