结直肠癌肝转移机制的研究进展  

Mechanism of liver metastasis in colorectal cancer

作　　者：王浩[1] 陆培华[1] 陶国青[1] 

机构地区：[1]南京医科大学附属无锡市人民医院普通外科,无锡214000

出　　处：《国际肿瘤学杂志》2011年第9期700-703,共4页Journal of International Oncology

摘　　要：肝脏是结直肠癌转移的主要靶向器官，越来越多的研究证明，肿瘤微环境、信号传导途径、染色体的异常、增殖与凋亡调控基因的异常等为结直肠癌肝转移的重要的机制，结直肠癌肝转移是其共吲作用的结果。研究其机制能为预防和治疗结直肠癌肝转移提供新思路。Liver is the main target organ of the metastasis of colorectal cancer. More and more researches demonstrate that including micro-environment of cancer, signal transduction pathway, abnormality of chromosomes and the gene which control cell proliferation and apoptosis are the most important mechanisms in liver metastasis of colorectal cancer. The metastasis of colorectal cancer is the result of all these factors. To study the mechanism can shed some light on prevention and therapy in liver metastasis of colorectal cancer.

关 键 词：结直肠肿瘤 肿瘤转移 

分 类 号：R735.34[医药卫生—肿瘤]