保健食品中违法添加9种苯二氮卓草类化合物的检测方法  

Method for Testing 9 Kinds of Benzodiazepines Illegally Added in Health-care Food

作　　者：刘杜妙[1] 翁雪萍[1] 林暖丹[1] 

机构地区：[1]广东省惠州市药品检验所,惠州516003

出　　处：《中国药事》2011年第9期874-876,共3页Chinese Pharmaceutical Affairs

基　　金：2009年广东省食品药品监督管理局系统药品监督抽验课题研究项目(编号YJ200924)

摘　　要：目的建立检测保健食品中违法添加9种苯二氮类化合物的方法。方法采用HPLC法对具有镇静安神功效的保健食品进行检测,并通过液质联用进行确证。结果 67批样品经HPLC法与液质联用确证后发现有13批样品非法添加了苯二氮类化合物。结论此方法可作为保健食品中违法添加9种苯二氮草卓类化合物样品的检测。Objective To establish a method for testing 9 benzodiazepines illegally added in health-care food.Methods Using HPLC method to test the health-care food with sedative effect,and through the use of LC-MS to confirm.Results Through the HPLC and the LC-MS,13 batches of samples illegally added were found in 67 batches of samples.Conclusion The method can be used to test 9 kinds of benzodiazepines illegally added in health-care food.

关 键 词：苯二氮类 HPLC 液质联用 

分 类 号：R155.5[医药卫生—营养与食品卫生学] R927.1[医药卫生—公共卫生与预防医学]