直肠癌根治术后肝转移的危险因素分析  

Analysis of Risk Factors for Hepatic Metastasis from Rectal Cancer after Radical Excision

作　　者：孙海燕[1] 王言青[2] 邢艳敏[1] 谢广茹[1] 

机构地区：[1]天津医科大学附属肿瘤医院中西医结合科天津市肿瘤防治重点实验室,天津300060 [2]天津市人民医院骨科

出　　处：《肿瘤防治研究》2011年第9期1046-1049,共4页Cancer Research on Prevention and Treatment

摘　　要：目的分析与直肠癌根治术后肝转移的间隔时间、转移方式相关的危险因素,以提高有利证据预测及预防肝转移的发生。方法回顾性分析天津医科大学附属肿瘤医院自1995年收治的143例直肠癌患者,分析直肠癌根治术后肝转移发生间隔时间与肝转移方式的危险因素。结果原发肿瘤分化程度、Dukes分期及合并肝外转移情况与间隔时间有独立相关性。而肿瘤侵犯深度则是肝转移方式的独立危险因素。结论我们可以用原发肿瘤分化程度、Dukes分期及合并肝外转移情况估计直肠癌根治术后肝转移间隔时间,而肿瘤侵犯深度可用来估计肝转移方式。Objective To analyze the risk factors for interval time Pattern of hepatic metastases from rectal cancer after radical surgery and provide supportive evidence for predicting and preventing hepatic metastasis from rectal cancer after radical surgery.Methods A retrospective study of 143 patients with hepatic metastasis from rectal cancer after radical surgery from 1995 to 2010.The data was analyzed to evaluate significant risk factors for interval time.Pattern of hepatic metastasis from rectal cancer after radical surgery.Results The histologic differentiation,Dukes criteria and extrahepatic metastasis were independently correlated with the interval time of hepatic metastasis,while the depth of invasion was independently correlated with the pattern of hepatic metastasis.Conclusion We could evaluate the interval time of hepatic metastasis with the histologic differentiation,Dukes criteria and extrahepatic metastasis,while the depth of invasion could be used to evaluate the pattern of hepatic metastasis from rectal cancer in patients with radical surgery.

关 键 词：直肠癌 肝转移 间隔时间 

分 类 号：R735.37[医药卫生—肿瘤]