富血小板血浆在颌骨再生方面的应用  

Application of platelet-rich plasma in the regeneration of jaw

作　　者：赵春苗[1] 李鹏[1] 陈博[1] 余擎[1] 

机构地区：[1]第四军医大学口腔医学院,陕西西安710032

出　　处：《牙体牙髓牙周病学杂志》2011年第9期536-540,共5页Chinese Journal of Conservative Dentistry

摘　　要：富血小板血浆(platelet-rich plasma,PRP)是全血经过密度梯度离心分离产生的血小板浓缩物,富含多种自源性生长因子,不仅具有促进组织愈合和骨再生的作用,而且还避免了免疫原性和疾病传播等缺点。迄今为止,国内外学者对PRP已进行了大量的基础和临床研究,该文就其生物学特性、在颌骨再生和其他方面的应用研究作一综述。Platelet-rich plasma（PRP） is blood plasma concentrates which are produced by whole blood after density gradient centrifugation.PRP is rich in self-derived growth factors.PRP not only promotes tissue healing and bone regeneration,but also overcomes the weaknesses of immunogenicity and disease tramsmission.So far,many researchers both at home and abroad have done a lot of basic and clinical researches about PRP.This article will review PRP’s biological characteristics and its application studies in the regeneration of jaws and other fields.

关 键 词：富血小板血浆 血小板源性生长因子 转化生长因子-Β 成纤维细胞生长因子 骨再生 

分 类 号：R780.2[医药卫生—口腔医学]