中国城市<17岁健康人群末梢血铁元素水平分析  

Iron content in peripheral blood among healthy people aged 1 to 17 years in cities of China

作　　者：张治青[1] 王玉[1] 赵波 温晓玲 马剑华[1] 张印红[1] 

机构地区：[1]兰州大学公共卫生学院营养与食品研究所,甘肃兰州730000 [2]成都妇幼保健院 [3]广州市花都区妇幼保健医院

出　　处：《中国公共卫生》2011年第10期1316-1317,共2页Chinese Journal of Public Health

摘　　要：目的建立中国大中城市0~17岁健康人群末梢血铁元素临床参考值范围数据库,并分析其与年龄、性别的相关性。方法随机抽取全国9个大中城市的101 600名0~17岁健康人,采用原子吸收光谱法进行测定,利用SPSS 16.0软件分析检测结果,百分位数法确定参考值范围。结果末梢血铁含量随年龄增长逐渐增高,平均含量为（7.51±0.78）mmol/L,各年龄组间差异有统计学意义（P〈0.05）,婴儿组、学龄组和青春期组性别间差异有统计学意义（P〈0.05）;为临床应用方便,分别确定了各年龄组的期望参考值范围（P16~P84）：婴儿组男性：6.37~7.82 mmol/L,婴儿组女性：6.42~7.81 mmol/L;幼儿组：6.72~8.17 mmol/L,学龄前组：7.07~8.51mmol/L;学龄组男性：7.29~8.67mmol/L,学龄组女性：7.20~8.63mmol/L;青春组男性：7.72~9.35mmol/L,青春组女性7.29~8.80mmol/L。临界参考值范围（P2.5~P97.5）：婴儿组男性：5.64~8.54mmol/L,婴儿组女性：5.72~8.57mmol/L;幼儿组：5.99~8.92mmol/L,学龄前组：6.36~9.26mmol/L;学龄组男性：6.57~9.44mmol/L,学龄组女性：6.51~9.42mmol/L;青春组男性：6.81~10.08mmol/L,青春组女性：6.59~9.58mmol/L。结论调查0~17岁健康人末梢血铁元素水平可为制定大中城市健康人末梢血铁元素参考值范围提供参考,为临床诊断提供依据。Objective To establish a database for reference range of iron content in peripheral blood among urban healthy people and to analyze the correlation betweem iron content and age and gender.Methods Totally 101 600 persons aged 0-17 years were sampled from nine cities.The iron conternt in peripheral blood was determined with atomic absorption spectroscopy.The reference range of the iron content was established with percentiles method and the data were analyzed with SPSS16.0.Results The iron conternt in peripheral blood increased with age with an average level of 7.51±0.78 mmol/L.There were significant differences in iron content among different age groups(P<0.05).There were significant gender differences in the content among the infants,school-age children,and puberty adolescents.The reference values of the iron content(percentiles 16-84,mmol/L) for different gender and age groups were 6.37-7.82 for male infants,6.42-7.81 for female infants,6.72-8.17 for young children,7.07-8.51 for preschool children,7.29-8.67 for male school-age children,7.20-8.63 for female school-age children,7.72-9.35 for male puberty addescents,and 7.29-8.80 for female puberty adolescents,respectively.The critical reference vlues of the iron content(percentiles 2.5-97.5,mmol/L) were 5.64-8.54 for male infants,5.72-8.57 for female infants,5.99-8.92 for young children,6.38-9.28 for male preschool children,6.35-9.25 for female preschool children,6.57-9.44 for male school-age children,6.51-9.42 for female school-age childrem,6.81-10.08 for male puberty abolescents,and 6.95-9.58 for female puberty adolescents,respectively.Conclusion The results of the survey provide reference values of peripheval blood iorn for urban people aged 1-17 years for the diagnosis of iron deficiency in clinical practice.

关 键 词：末梢血 铁 参考值 

分 类 号：R153.2[医药卫生—营养与食品卫生学]