乙肝肝硬化中医证型与血清CHE相关性研究  

Associativity Research between Patterns of TCM Syndromes in Hepatic Cirrhosis from Type B Hepatitis and Serum CHE

作　　者：梅国进[1] 张心海（指导） 

机构地区：[1]泸州医学院,四川646000 [2]不详

出　　处：《山西中医》2011年第10期13-14,共2页Shanxi Journal of Traditional Chinese Medicine

摘　　要：目的:研究乙肝肝硬化各中医证型与CHE的相关性。方法:对符合诊断和排除标准的入选患者进行中医辨证,分为5个常见证型,100例患者进行血清胆碱酯酶检测,探讨其与乙肝肝硬化中医证型的内在联系。结果:CHE水平肝气郁结组最高,湿热内蕴及脾虚湿盛组次之,之后为脾肾阳虚,肝肾阴虚证组最低。结论:乙肝肝硬化临床以脾虚湿盛及肝气郁结多见。肝气郁结证处于肝硬化的初期,肝脏储备功能尚可,血清CHE水平较高;肝肾阴虚证多属乙肝肝硬化终末期,肝功损害严重,肝脏储备功能低下,CHE水平降低。而脾虚湿盛、湿热内蕴证属于疾病中期病情较稳定;脾肾阳虚证多属肝硬化病程中后期,血清CHE水平较低。血清CHE对于判断肝硬化中医证型及判断肝硬化肝脏储备、辨别疾病所处阶段具有重要价值。Objective： To investigate the correlation between the patterns of TCM syndromes and CHE in hepatic cirrhosis from type B hepatitis. Method： The selected cases associated with diagnostic and exclusion code were differentiated with symptoms and signs for classification of syndrome, and 5 common patterns of syndrome were determined. 100 patients were tested by serum cholinesterase testing, and the internal relations were investi- gated between serum cholinesterase and the patterns of TCM syndrome in hepatic cirrhosis from type B hepatitis. Results： CHE was the highest in group of liver qi stagnation, higher in group of endoretention of damp heat and group of damp abundance due to splenic asthenia, followed by group of asthenic splenonephro - yang, and the lowest in group of hepatic and renal yin deficiency. Conclusion： Syndrome of liver qi stagnation and syndrome of damp abundance due to splenic asthenia are more common in hepatic cirrhosis from type B hepatitis in clinic. Syndrome of liver qi stagnation shows up in the early stage of cirrhosis, liver functional reserve is acceptable, and serum CHE is higher. Syndrome of hepatic and renal yin deficiency is mostly in the end stage of liver cirrhosis, in which liver damage is severe, liver has dysfunctional reserve, and CHE is in low level. Syndrome of damp abundance due to splenic asthenia and syndrome of endoretention of damp heat are in the mid - term in which the patient＇s condition is more stable. Syndrome of asthenic splenonephro -yang is mostly in the late course of cirrhosis, and serum CHE is in low level. Serum CHE has an important value to judge patterns of TCM syndrome in cirrhosis, to determine the liver functional reserve in cirrhosis, and to identify the stage of the disease.

关 键 词：乙肝肝硬化 中医证型 CHE 临床研究 

分 类 号：R575.2[医药卫生—消化系统]