木糖醇改善^(13)C-尿素呼气试验患者的依从性研究  

Xylitol improves compliance of patients to ^(13)C-urea breath test

作　　者：李园[1] 吴本俨[1] 

机构地区：[1]解放军总医院南楼消化科,北京100853

出　　处：《军医进修学院学报》2011年第10期1032-1033,共2页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的观察木糖醇对13C-尿素呼气试验检测试剂的口感及DOB检测值的影响。方法 120例病人同时进行不添加和添加木糖醇0.05g和0.10g组,自评检测的试剂口感,并配对检验两次检测的DOB值变化。结果木糖醇0.05g组和0.10g组,口感可接受百分比分别为43.3%和66.7%,显著高于未添加木糖醇时检测(分别为20.0%和33.3%,P<0.05),添加木糖醇0.10g口感可耐受百分比显著高于添加0.05g组(P<0.05)。两种剂量木糖醇对DOB检测值均无显著性影响(P>0.05)。结论在13C-尿素呼气试验检查试剂中加入适量木糖醇可改善口感、提高病人依从性、其中添加0.10g木糖醇效果最优,对13C-尿素呼气试验的DOB值无影响。Objective To observe the effect of xylitol on the texture of reagents used in 13C-urea breath test and the value of DOB test.Methods One hundred and twenty patients were randomly divided into 0.05g or 0.10g xylitol group and non xylitol group.Texture of reagents used in 13C-urea breath test was assessed by the patients themselves in the xylitol group.DOB value was detected twice by paired test.Results The acceptable texture was significantly higher in 0.05g and 0.10g xylitol group than in non xylitol group（43.3% and 66.7% vs 20.0% and 33.3%,P0.05） and in patients receiving 0.10g xylitol than in those receiving 0.05g xylitol（P0.05）.However,no difference was observed in DOB value between patients receiving 0.05g or 0.10g xylitol（P0.05）.Conclusion Adding an appropriate amount of xylitol can improve the texture and compliance of patients to 13C-urea breath test.The best result can be achieved by adding 0.10g xylitol with no effect on the DOB value in 13C-urea breath test.

关 键 词：螺杆菌 幽门 ^13C-尿素呼气试验 木糖醇矫味剂 依从性 

分 类 号：R573[医药卫生—消化系统]