注射用丹参粉针剂治疗溃疡性结肠炎患者出凝血时影响  

Effect of Danshen Lyophilized Powder for Injection on Thromboxane Function of Ulcerative Colitis Patients

作　　者：刘伟[1] 刘允[1] 张春阳[1] 张雪[1] 何磊[1] 李露[1] 

机构地区：[1]沈阳市肛肠医院,辽宁沈阳110002

出　　处：《中华中医药学刊》2011年第10期2304-2305,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：辽宁省科技厅资助项目(2009225010-50)

摘　　要：目地:观察注射用丹参对溃疡性结肠炎的疗效及对出凝血时的影响。方法:符合纳入标准的患者被随机分到注射用丹参治疗组和西药常规治疗组。治疗结束后,观察两组治疗效果,测定治疗前后患者出凝血时(PT、APTT、Fbg)及血小板(PLT)水平。结果:丹参治疗组有效率为95.69%,对照组为82.05%,两者比较差异具有统计学差异(P<0.05);两组治疗前后PT、APTT、Fbg、PLT水平差异均有统计学差异(P<0.05),并且丹参治疗组改善效果更明显(P<0.05)。结论:联合应用注射用丹参能提高溃疡性结肠炎疗效,并能改善患者高凝状态。Objective：To observe the therapeutic efficacy of Danshen Lyophilized Powder for injection on uicerative Colitis Patients and the effect on thromboxane function.Methods：The patients were classified into two groups.One group（control group） were recievecd the conventional therapy,Danshen Lyophilized Powder for Injection was used as the basis of the conventional therapy on the other group（treatment group）.After being treated,the therapeutic efficacy was observed and the thromboxane function was detected.Results：The effective power of treatment group was 95.69% and the effective power of control group was 82.05%,The difference between them was significant（P0.05）.The levels of PT,APTT,Fbg,PLT between them were significant too（P0.05）.Conclusion：Danshen Lyophilized Powder for Injection can increase the therapeutic efficacy of ulcerative colitis patients and improve the hypercoagulabale state.

关 键 词：溃疡性结肠炎 活血化瘀法 注射用丹参 

分 类 号：R574.62[医药卫生—消化系统]