帕罗西汀对老年脑卒中后运动康复的影响  

Effects of Paroxetine on Exercise Rehabilitation after Stroke in Aged Patients

作　　者：潘宁[1] 付海燕[1] 

机构地区：[1]山东大学附属省立医院,250022

出　　处：《中西医结合心脑血管病杂志》2011年第10期1196-1197,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的探讨帕罗西汀对老年性脑卒中后运动康复的影响。方法将64例患者按入院顺序随机分为治疗组和对照组各32例。对照组给予脑卒中常规治疗,治疗组在对照组治疗基础上加服帕罗西汀20 mg/d,连续90 d,两组患者同时接受物理治疗。治疗前及治疗后21 d、90 d进行功能独立性评定量表(FIM)评估。结果治疗前和治疗后21 d两组FIM评分差异无统计学意义(P>0.05),治疗后90 d治疗组FIM评分值较治疗前显著升高(P<0.01),且高于对照组(P<0.05)。结论帕罗西汀治疗脑卒中后运动功能障碍安全有效,可促进运动功能康复。Objective To evaluate the clinical effect of paroxetine on exercise rehabilitation after stroke in aged patients（pts）.Methods Sixty-four aged pts with stroke were randomly divided into paroxetine group（n=32） treated with paroxetine 20 mg/d for 90 days and routine treatment,and control group（n=32） received only routine treatment.The functional independence measure（FIM） was assessed before and after treatment.Results FIM score at 90 days was significantly increased in paroxetine group（P0.01）,which was more than that in control group（P0.05）.Conclusion The result suggests paroxetine is effective and safe in the treatment of motor dysfunction after stroke and enhance motor function recovery.

关 键 词：帕罗西汀 脑卒中 运动康复 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R255.2[医药卫生—临床医学]