乳腺癌DSA造影及术前超选择性动脉化疗栓塞  

Breast cancer DSA and preoperative super-selective transarterial chemoembolization

作　　者：许彪[1] 庄亚强[1] 刘惕生[1] 陈刚[1] 韦力谦[1] 

机构地区：[1]广西医科大学第五附属医院放射科介入室,柳州545006

出　　处：《介入放射学杂志》2011年第9期696-699,共4页Journal of Interventional Radiology

基　　金：广西区卫生厅科技计划项目(Z2008413)

摘　　要：目的探索乳腺癌的血供特点及术前超选择性动脉化疗栓塞的临床应用价值。方法 48例经穿刺活检确诊乳腺癌患者,采用术前DSA造影评估乳腺癌供血动脉分布,分别超选择性插管化疗栓塞。结果 48例患者DSA造影共发现74支明确供血动脉。单支供血9例,多支供血39例,主要以胸外侧动脉和(或)胸廓内动脉为主。灌注化疗后手术切除的近期疗效:有效率(CR+PR)为93.8%(45/48)。中位缓解期为17个月,中位生存期为38个月。结论乳腺癌的供血动脉与肿瘤的位置密切相关,外侧乳腺癌主要由胸外侧动脉主导供血,内侧乳腺癌主要由胸廓内动脉主导供血,乳腺癌术前超选择性插管,靶血管区域化疗栓塞可明显提高化疗栓塞的针对性和术前介入治疗的疗效。Objective To evaluate the blood supply of breast cancer with DSA and to discuss the clinical application of preoperative super-selective transarterial chemoembolization.Methods The blood supply of breast cancer was evaluated with DSA in 48 patients with biopsy-proved breast cancer.The arterial blood-supply distribution of breast cancer was analyzed.Super-selective catheterization and arterial chemoembolization was performed.Results A total of 74 blood-supplying arteries were detected on DSA in 48 patients.Single feeding artery was seen in 9 cases,while multiple feeding arteries were seen in 39 cases.The feeding arteries mainly were the lateral thoracic artery and internal thoracic artery.The short-term curative effectiveness,including CR and PR,was 93.8%（45/48）.The median period of remission was 17 months,and the median survival time was 38 months.Conclusion A significant correlation exists between the site of breast cancer and the origin of feeding arteries.The laterally-located breast cancer gets its blood supply mainly from the lateral thoracic artery,while the medially-located breast cancer gets its blood supply mainly from the internal thoracic artery.Preoperative super-selective catheterization and regional target vascular chemoembolization can significantly increase the curative effectiveness.

关 键 词：乳腺癌 化疗栓塞 动脉插管 

分 类 号：R737.9[医药卫生—肿瘤]