人造革厂工人二甲基甲酰胺经皮接触评估研究  

Assessment of dermal exposure to N＇N-dimethyl formamide in synthetic leather workers

作　　者：徐承敏[1] 唐红芳[1] 路艳艳[1] 柴剑荣[1] 吴昊[1] 钱亚玲[1] 

机构地区：[1]浙江省医学科学院卫生学研究所,杭州310013

出　　处：《中华劳动卫生职业病杂志》2011年第9期707-709,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：浙江省科技厅项目（2006F12036）;浙江省卫生厅科学研究基金项目（20068004）

摘　　要：目的对人造革厂工人经皮肤接触二甲基甲酰胺（DMF）的水平进行评估。方法采用洗手法和擦拭法对某人造革厂湿法配料、湿法涂台和三版印刷工人进行皮肤接触水平监测，同时对工人的吸入水平及尿中甲基甲酰胺（NMF）水平进行检测。结果所有洗手液和擦拭液样品中均检测出DMF（洗手液：0．35～15．34mg；擦拭液：29．58—110．45μg）。在洗手试验组中，洗手液中DMF总量与作业人员班末尿中NMF含量、累积接触水平与班末尿中NMF含量呈对数相关性；擦拭试验组中则各指标间无相关性。结论洗手法是一种较好的研究DMF作业人员皮肤接触水平的方法，具有容易在现场实施以及结合生物监测结果等优点。Objective To assess the dermal exposure levels of N＇N-dimethylformamide （DMF） in synthetic leather workers. Methods Potential dermal exposure levels of DMF was measured with skin wiping and hand washing samples in printing workers. The DMF concentration in personal air samples and urinary NMF were also detected. Results DMF was detected in all the hand washing （0.35-15.34 mg DMF） and skin wiping （29.58-110.45 μg DMF） samples. DMF level in hand washing samples and cumulative exposure level were correlated with NMF level in urine after logarithm transform. There was no good correlation between the DMF level of skin wiping samples and the urinary NMF level. Conclusion The sampling method of hand washing is a reasonable method to determine dermal exposure level.

关 键 词：二甲基甲酰胺 危险性评估 环境监测 

分 类 号：TS[轻工技术与工程]