66例胃癌手术临床特点及预后影响因素分析  

Analysis on clinical characteristics and prognosis in 66 cases with gastric cancer after operation

作　　者：陈兵[1] 文西年[1] 袁建明[1] 

机构地区：[1]新疆医科大学第一附属医院胃肠肿瘤外科,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2011年第7期747-749,共3页Journal of Xinjiang Medical University

摘　　要：目的探讨因胃癌行手术治疗患者的生存情况及其预后的影响因素。方法回顾性分析2002年1月～2006年11月在新疆医科大学第一附属医院胃肠肿瘤外科行手术治疗的66例胃癌患者的临床资料。采用Kaplan-Meier生存率分析和Cox比例风险模型进行单因素和多因素分析。结果 66例胃癌患者的1、3、5年生存率分别为68.0%、44.0%、11.0%。单因素分析显示PTNM分期、肿瘤浸润深度、淋巴结转移、有无远处转移、根治度是影响术后生存率的因素。Cox多因素分析显示,胃癌患者行手术治疗后的独立影响因素为根治度、PTNM分期及有无远处转移的交互作用。结论 TNM分期及有无远处转移是影响胃癌患者预后的最重要因素。加强宣传、早期发现对改善胃癌患者手术后的预后有重要意义。Objective To analyze clinicopathological characteristics and the prognosis of gastric cancer patients after opertion.Methods Combined with follow-up,66 gastric cancer cases who had underwent operation in our hospital from January 2002 to December 2006 were retrospectively analyzed.Kaplan-Meier analysis was used for the univariate analysis,and Cox regression analysis was used for multivariable analysis.Results Survival rates of the patients after radical resection with 1,3 and 5 year were 68.0%,44.0%,11.0% respectively.The univariate analysis showed that the healing degrees in the gastric cancer,PTNM classification,invason depth,lyphon node metastasis,distant metastasis were correlated with survival rates（P0.05）.Multivariable analysis showed that the healing degrees in the gastric cancer,TNM classification,distant metastasis were independent prognostic factors of gastric cancer（P0.05）.Conclusion TNM classification and distant metastasis were the most important prognostic factors affecting gastric cancer.Strengthening propaganda and early detection may improve prognosis for gastric cancer.

关 键 词：胃肿瘤 预后 COX多因素分析 

分 类 号：R735.2[医药卫生—肿瘤]