低T3综合征与重症急性胰腺炎预后的相关性研究  

Case-control study between low-T3 syndrome and prognosis of severe acute pancreatitis

作　　者：傅蓉[1] 杨庆渝[1] 李和莅[1] 

机构地区：[1]成都市第二人民医院急诊科,四川成都610017

出　　处：《西部医学》2011年第10期1940-1942,共3页Medical Journal of West China

摘　　要：目的探讨低T3综合征与重症急性胰腺炎预后的关系。方法选取156例重症急性胰腺炎患者,以重症急性胰腺炎患者的死亡为因变量,均分为死亡组与生存组(未死亡者)各78例,运用logistic回归评价低T3综合征与重症急性胰腺炎预后的关系。结果低T3综合征56例占全部样本的35.90%,与生存组相比,死亡组的患者有更高的Ranson评分分数(t=-6.053,P=0.000),较多的低T3综合征(χ2=8.345,P=0.004)和多器官功能障碍的发生率(χ2=12.857,P=0.000)。多因素logistic回归显示低T3综合征(OR=2.865,95%CI 1.226to 6.694)、Ranson分数(OR=2.183,95%CI 1.553to 3.069)、多器官功能障碍(OR=6.570,95%CI 2.364to 18.259)及血液浓缩(OR=2.713,95%CI 1..023to 7.195)等是重症急性胰腺炎死亡的危险因素。结论低T3综合征可能是重症急性胰腺炎死亡的危险因子,对其监测及治疗,可能会改善重症急性胰腺炎的预后。Objective To assess whether low-T3 syndrome is a risk factor of poor prognosis among inpatients with severe acute pancreatitis（SAP） or not.Methods Inpatients with SAP were included and divided into death patients（78 cases） and survival patients（78 cases）.Logistic model analysis was used to assess the association low-T3 syndrome and SAP.Results 78 pairs＇ patients were included.Death patients had higher Ranson score,more low-T3 syndrome,and higher prevalence of multisystem and organ failure（MSOF）（P0.05）.Logistic analysis demonstrated that low-T3 syndrome,Ranson score,MSOF,and pachyemia may be associated with poor prognosis among inpatients with SAP.Conclusion Low-T3 syndrome may be a risk factor of poor prognosis among inpatients with SAP.Self monitoring and management for low-T3 syndrome may improve cognitive impairment.

关 键 词：低T3综合征 重症急性胰腺炎 预后 死亡 相关性研究 

分 类 号：R576[医药卫生—消化系统]