显微CT技术对颌骨骨小梁解剖结构的测量及其准确性评价  

Measurement of anatomical structure of jaw bone trabecula with micro-CT and its accuracy evaluation

作　　者：金光春[1] 张晓燕[1] 姜玲[1] 李祥林[1] 张迪[1] 黎卫星[1] 金熙真[2] 金东春[3] 

机构地区：[1]滨州医学院口腔学院,山东烟台264003 [2]韩国延世大学口腔解剖学教研室 [3]延边大学动物医学系,吉林延吉133002

出　　处：《吉林大学学报（医学版）》2011年第5期833-837,共5页Journal of Jilin University：Medicine Edition

基　　金：山东省科技厅自然科学基金重点支持项目资助课题(Z2006C01);教育部留学回国人员科研启动基金;校级学科带头人培养与科研启动项目资助课题(BY2005XSGG009;BY2005KYQD16)

摘　　要：目的:应用显微CT(micro-CT)测量颌骨解剖结构,探讨micro-CT测量的准确性。方法:将9具尸体的下颌骨标本分为髁状突组(3个标本,骨小梁结构均匀)和下颌骨体部组(5个标本,骨小梁结构不均匀),图像分析软件建立总共30个有效容(VOI),每组各15个。计算每个像元大小的每个参数的平均值和标准差,并用方差分析判断不同参数值之间差异是否有统计学意义。结果:在所有重建像元大小中,下颌骨体部组的结构模型指数(SMI)与18μm像元组比较差异有统计学意义(P<0.05)。髁状突组中重建像元大小为36μm时未发现差异有统计学意义(P>0.05),在所有重建像元大小中,骨小梁厚度(Tb.Th)、骨小梁数量(Tb.N)和骨小梁分离度(Tb.Sp)在下颌骨体部组和髁状突组比较差异均具有统计学意义(P<0.05)。其他大部分参数在像元大小为36μm时比较差异均无统计学意义。在下颌骨体部组,所有参数在不同的像元大小下比较差异均有统计学意义(P<0.05)。结论:micro-CT的观测均能较准确反映骨小梁解剖结构的变化。Objective To measure the anatomic structures of the jaw and to discuss the accuracy of the method.Methods The mandibular specimens were divided into ankle conylar group（3 specimens,regular trabecular architecture and mandibular body group（5 specimens,irregular trabecular architecture）.Fifteen volumes of interests（VOI） were created in each group and the total of thirty were measured.The mean value and standard deviation of each parameter at each reconstruction voxel size were calculated.Repeated ANOVA test was used to determine whether the significant differences in the values existed between each parameter.Results The structure model index（SMI） value in mandibular body group had significant difference（P0.05） at all reconstruction voxel sizes compared with 18 μm group;but in condyle group,the reconstruction voxel size of 36 μm was not significant（P0.05）.The differences of trabecular thickness（Tb.Th）,trabecular number（Tb.N） and trabecular seperation（Tb.Sp） values btween condyle and mandibular body groups were significant at all reconstruction voxel sizes（P0.05）.In condyle group,except for Tb.Th,Tb.N,and Tb.Sp,the most parameter values were not significant at reconstruction pixel size of 36 μm.In the mandible body group,the differences of all parameter values between different pixel sizes were significant.Conclusion Micro-CT can reflect the anatomical changes of bone trabecula structure.

关 键 词：颌骨 显微CT 骨小梁 解剖学 

分 类 号：R813[医药卫生—放射医学]