APS-B数字荧光素眼底血管造影及图像分析系统检测视网膜黄斑中心凹无血管区面积及其意义  

Measurement of macular center retina of area by APS-B digital fluorescein fundus angiography and image analysis system and its significance

作　　者：李迪[1] 孟壮志[1] 刘海英[1] 李建国[1] 高振平[2] 

机构地区：[1]内蒙古民族大学医学院解剖学教研室,内蒙古通辽028000 [2]吉林大学白求恩医学院人体解剖学教研室,吉林长春130021

出　　处：《吉林大学学报（医学版）》2011年第5期906-908,共3页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技厅科研基金资助课题(200705353)

摘　　要：目的:通过数字荧光素眼底血管造影(FFA)及图像分析系统测量视网膜黄斑中心凹无血管区(FAZ)的面积,为临床工作提供正常形态学数据及技术方法。方法:采用数字FFA检查37例无眼疾就诊者中的49只正常眼,研究对象均具有屈光间质清晰、中心凹无视网膜出血等视网膜疾病。使用APS-B图像分析系统计算FAZ面积等指标,比较年轻组与老年组FAZ面积的差异性,分析年龄与FAZ的相关性。结果:正常人的FAZ面积均值为(0.32±0.09)mm2,年轻组FAZ平均面积为(0.23±0.07)mm2,老年组的FAZ平均面积为(0.26±0.11)mm2,2组间比较差异无统计学意义(P>0.05);年龄增长与黄斑面积之间无相关性(r=0.312,P=0.106),但FAZ面积个体间存在较大差异。结论:运用APS-B数字FFA及图像分析系统得出的FAZ面积不会随着年龄的增长而发生变化。Objective To measure the area of macular foveal avascular zone（FAZ） without area vasculosa with APS-B digital fluorescein fundus angiography（FFA） and image analysis system,and provide the normal morphological data and technique for clinical work.Methods The 49 normal eyes in 37 cases without eye diseases were detected with digital FFA.All objects of the study had clear dioptric media without retinal disease,such as retinal hemorrhage in center of retina.The area of FAZ was calculated with APS-B image analysis system;the difference FAZ areas between yonger age group and older age group was compared,then the correlationship between age and FAZ area was analyzed.Results The normal FAZ area was（0.32±0.09） mm2,and it was（0.23±0.07） mm2 in yonger age group,and the FAZ area in older age group was（0.26±0.11） mm2.There was no significant difference between two groups（P0.05）.There was no correlationship between age increasing and macular area（r=0.312,P=0.106）,but there were greater differences of FAZ area between individuals.Conclusion The FAZ area obtained with APS-B digital FFA and image analysis system doesn＇t change with age increasing.

关 键 词：黄斑 黄斑中心凹无血管区 荧光素眼底血管造影 

分 类 号：R774.5[医药卫生—眼科]