经支气管镜确诊的2168例肺癌的临床特点分析  

Analysis of Clinical Features of 2 168 Confirmed Cases of Lung Cancer Diagnosed by Bronchoscopy

作　　者：张宇[1] 于力克[1] 谢海燕[1] 胡韦华[1] 郝可可[1] 夏宁[1] 

机构地区：[1]南京市胸科医院呼吸一科,南京210029

出　　处：《中国医科大学学报》2011年第10期930-933,共4页Journal of China Medical University

摘　　要：目的分析经支气管镜确诊肺癌的临床特点。方法回顾性分析经支气管镜确诊为肺癌的2168例患者的性别、年龄、病理类型、病变部位、镜下表现、取材方法等特点.结果该组患者男女比例为4．8：1，60～69岁为发病年龄高峰。鳞癌是最主要的病理类型（占44．56％），其次为腺癌（占25．92％）和小细胞癌（占18．27％）。男性鳞癌发病率最高（占50．61％），女性腺癌发病率最高（占56．18％）。钳检、刷检、支气管肺泡灌洗、经支气管镜针吸的诊断阳性率分别为81．60％、49．37％、18.24％和62．65％，钳检联合刷捡阳性率为89．06％。结论支气管镜检查是诊断肺癌的重要手段。不同年龄、不同性别的肺癌患者发病不同，病理类型分布有差别。重视支气管镜检查和提高活检技术，可显著提高诊断率，早期诊断肺癌，为临床治疗提供依据。Objective To investigate the clinical characteristics of confiruled cases of lung cancer diagnosed by bmnchoscopy. Methods A retrospective analysis was conducted to study the clinical features such as gender, age, pathologic type,lesion location, bronchoscopic image and sampling method of 2,168 confirmed cases of lung cancer diagnosed by bronchoscopy. Results The sex ratio （M/F） was 4.8 ： 1 and the peak incidence was between 60 to 69 years of age. The most common pathologic type was squamous cell carcinoma （44.56%）,tollowed by adenocarcinoma （25.92%） and small cell lung cancer （18.27%）. Squamous cell carcinoma had the highest incidence rate （50.61%） among men, while adenocareinoma had the highest rate among women （56.18%）. The positive rotes diagnosed by forceps biopsy, brash biopsy, bronchial alveolar lavage and transbronehial needle aspiration were 81.60% ,49.37%, 18.24% and 62.65% respectively. The positive rate by forceps biopsy combined with brush was 89.06%. Conclusion Bronchoscopy is an important approach in the diagnosis of lung cancer. The incidence and pathologic type of lung cancer vary depending on age and gender. Bronchoscopy and improving biopsy technique can markedly increase the diagnostic rate and help in early diagnosis of lung cancer.

关 键 词：肺癌 支气管镜 诊断 

分 类 号：R734.2[医药卫生—肿瘤]