Current therapeutic strategies for premature ejaculation and future perspectives  

作　　者：Zhong-Cheng Xin Yi-Chen Zhu Yi-Ming Yuan Wan-Shou Cui Zhe Jin Wei-Ren Li Tao Liu 

机构地区：[1]Andrology Centre of Peking University First Hospital, Peking University, Beijing 100034, China [2]Department of Urology, Beijing Friendship Hospital, Capital Medica University, Beijing 100050, China

出　　处：《Asian Journal of Andrology》2011年第4期550-557,共8页亚洲男性学杂志（英文版）

基　　金：ACKNOWLEDGMENTS This work was supported by the National Natural Science Foundation of China （No. 30772285） and the Beijing Municipal Science and Technology Commission Fund （No. Z08050703320000）.

摘　　要：Premature ejaculation （PE） is a common sexual disorder in men that is mediated by disturbances in the peripheral and central nervous systems. Although all pharmaceutical treatments for PE are currently used ＇off-label＇, some novel oral agents and some newer methods of drug administration now provide important relief to PE patients. However, the aetiology of this condition has still not been unified, primarily because of the lack of a standard animal model for basic research and the absence of a widely accepted definition and assessment tool for evidence-based clinical studies in patients with PE. In this review, we focus on the current therapeutic strategies and future treatment perspectives for PE.Premature ejaculation （PE） is a common sexual disorder in men that is mediated by disturbances in the peripheral and central nervous systems. Although all pharmaceutical treatments for PE are currently used ＇off-label＇, some novel oral agents and some newer methods of drug administration now provide important relief to PE patients. However, the aetiology of this condition has still not been unified, primarily because of the lack of a standard animal model for basic research and the absence of a widely accepted definition and assessment tool for evidence-based clinical studies in patients with PE. In this review, we focus on the current therapeutic strategies and future treatment perspectives for PE.

关 键 词：5-HT DAPOXETINE premature ejaculation sexual disorder selective serotonin reuptake inhibitor TREATMENT 

分 类 号：TQ461[化学工程—制药化工] Q426[生物学—神经生物学]