脑梗死合并代谢综合征与脑动脉粥样硬化性狭窄的关系  

Relationship between cerebral artery atherosclerotic stenosis and metabolic syndrome in patients with acute cerebral infarction

作　　者：朱立勋[1] 徐海洲[1] 丁素菊[1] 

机构地区：[1]第二军医大学附属长海医院神经病科,上海市200433

出　　处：《江苏医药》2011年第18期2137-2139,共3页Jiangsu Medical Journal

摘　　要：目的探讨代谢综合征(MS)与脑动脉粥样硬化性病变的相关性。方法对74例因急性脑梗死入院的患者分为MS组(40例)及非MS组(34例)。借助经颅多普勒超声和(或)磁共振血管成像比较两组颅内外动脉粥样硬化性狭窄发生率。结果 MS组血管狭窄发生率为85.0%,明显高于非MS组的64.7%(P<0.05)。多元logistic回归分析示,MS与动脉粥样硬化无独立相关性,高密度脂蛋白胆固醇(HDL-C)与动脉粥样硬化独立相关(OR=0.071)。结论 MS与脑动脉粥样硬化性狭窄相关,但其危险性依赖于MS组中的低HDL-C血症。Objective To investigate the correlation of metabolic syndrome（MS） and atherosclerotic stenosis in patients with acute cerebral infarction（ACI）.Methods A total of 74 patients with ACI was divided into MS group（40 cases） and non-MS group（34 cases）.The incidences of intra-and extra-cranial atherosclerotic stenosis were measured with transcranical Doppler（TCD） and magnetic resonance angiography（MRA）.Results The incidence of atherosclerotic stenosis was higher in MS group than that in non-MS group（85.0% vs.64.7%）（P〈0.05）.Multiple logistic regression analysis indicated that the decreased HDL-C,but not the presense of MS,was an independent risk factor for cerebrovascular stenosis（OR=0.071）.Conclusion MS is associated with atherosclerotic stenosis and the drop of HDL-C is an independent risk factor in MS patients with ACI.

关 键 词：代谢综合征 急性脑梗死 脑动脉粥样硬化 

分 类 号：R743[医药卫生—神经病学与精神病学]