光合细菌转化槲寄生制剂乙醇提取浓度的研究  

Optimal level of ethanol for extraction of Mistletoe preparations transformed by photosynthetic bacteria

作　　者：漆小梅[1] 郑庆红[1] 杨官娥[1] 张肇铭[2] 

机构地区：[1]山西医科大学药学院,太原030001 [2]山西大学生命科学与技术学院

出　　处：《中国药物与临床》2011年第10期1113-1115,共3页Chinese Remedies & Clinics

基　　金：国家自然科学基金(30672621);山西省自然科学基金(2006011199;2010011048-2)

摘　　要：目的确定光合细菌(PSB)转化槲寄生制剂中槲寄生乙醇提取的最佳浓度。方法以荷Lewis肺癌小鼠为模型,以抑瘤率、免疫指标、抗氧化指标为标准进行筛选。结果 PSB转化槲寄生制剂的各项指标均优于单纯的槲寄生制剂,其中以PSB转化槲寄生制剂Ⅱ的各项指标为最佳。结论槲寄生75%乙醇提取物所制光合细菌转化槲寄生制剂为最佳。Objective To determine the optimal level of ethanol for extraction of mistletoe preparations transformed by photosynthetic bacteria（PSB）.Methods The screening of ethanol level was performed using mice model of Lewis-lung tumor and based on the tumor inhibition rate,immune parameters and antioxidation parameters.Results All parameters for PSB transformed mistletoe preparations were better than those for untransformed mistletoe preparations.Mistletoe preparations Ⅱ transformed by PSB showed the most favorable values of parameters.Conclusion PSB transformed mistletoe preparations extracted with 75% ethanol appears to be with best anti-tumor activity.

关 键 词：槲寄生 工艺学 光合细菌 抗肿瘤 

分 类 号：R285.5[医药卫生—中药学]