Efficient Synthesis of Functionalized Benzimidazoles and Perimidines： Ytterbium Chloride Catalyzed CmC Bond Cleavage  

作　　者：Cai, Lijian Ji, Xiaofeng Yao, Zhigang Xu, Fan Shen, Qi 

机构地区：[1]Key Laboratory of Organic Synthesis, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China

出　　处：《Chinese Journal of Chemistry》2011年第9期1880-1886,共7页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （Nos. 20872106, 20972107）.

摘　　要：An efficient method is developed for the synthesis of functionalized benzimidazoles and perimidines by the condensation of aryl diamines with β-carbonyl compounds catalyzed by ytterbium chloride. The reactions give good yields under mild conditions. A mechanism involving a lanthanide activated C--C bond cleavage is proposed.An efficient method is developed for the synthesis of functionalized benzimidazoles and perimidines by the condensation of aryl diamines with β-carbonyl compounds catalyzed by ytterbium chloride. The reactions give good yields under mild conditions. A mechanism involving a lanthanide activated C--C bond cleavage is proposed.

关 键 词：LANTHANIDE C--C activation catalysis ytterbium chloride BENZIMIDAZOLE PERIMIDINE 

分 类 号：TQ252.4[化学工程—有机化工] O626.23[理学—有机化学]