乳腺大汗腺癌临床病理及预后分析(附2例报道及文献复习)  

Clinicopathologic features and prognosis of breast apocrine carcinoma(Two cases report)

作　　者：胡祖健[1] 徐海滨[1] 何俊玲[1] 苏昆仑[1] 杨欧欧[1] 杨文伟[2] 

机构地区：[1]杭州市中医院乳腺科,浙江杭州310007 [2]杭州市中医院病理科,浙江杭州310007

出　　处：《实用肿瘤杂志》2011年第5期520-522,共3页Journal of Practical Oncology

摘　　要：目的探讨乳腺大汗腺癌的临床病理特征、诊断及预后。方法应用免疫组织化学方法检测乳腺大汗腺癌患者ER、AR和GCDFP-15的表达,同时复习国内外文献。结果乳腺大汗腺癌的临床表现如年龄分布、肿瘤部位以及肉眼形态和影像学特点与非大汗腺型乳腺癌无明显差别。乳腺大汗腺癌病理表现为肿瘤细胞具有大汗腺分化,免疫组织化学表现为较高的ER、PR阴性率和AR阳性。结论乳腺大汗腺癌是一种罕见的乳腺肿瘤,无特异性的临床特征,有特征性的病理改变,较好的预后。Objective To explore the clinicopathologic features,diagnosis and prognosis of breast apocrine carcinoma. Methods Breast apocrine carcinoma was diagnosed by morphology and detection of ER,AR,GCDFP-15 with immunohistochemistry,and the literatures were reviewed. Results Breast apocrine carcinoma had special pathological changes.The tumor was almost completely composed of apocrine cells,there were more high negative rates of ER and PR and positive AR in immunohistochemistry. Conclusions Breast apocrine carcinoma is a rare kind of breast tumors.It is characterized by pathologic changes and better prognosis,but there is no specific clinic feather.Its diagnosis mainly relies to morphology.

关 键 词：乳腺肿瘤/病理学 汗腺肿瘤 预后 免疫组织化学 

分 类 号：R737.9[医药卫生—肿瘤]