宫颈癌术后放射治疗232例回顾性临床分析  

Clinical research on postoperative radiotherapy for 232 patients with cervical cancer

作　　者：许曼[1] 魏丽春[1] 石梅[1] 龙晓丽[1] 刘隽悦[1] 王晓蒙[1] 罗山泉[1] 

机构地区：[1]第四军医大学西京医院放疗科,陕西西安710032

出　　处：《中华肿瘤防治杂志》2011年第16期1286-1289,共4页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:探讨宫颈癌患者术后放疗的疗效、并发症以及预后影响因素。方法:回顾性分析2006-01-01-2009-09-30在我科接受术后放疗的ⅠA～ⅡB期具有预后不良因素的232例宫颈癌患者。结果:3年总生存率、无瘤生存率和盆腔控制率分别为92.5%、89.2%和93.3%。无盆腔淋巴结转移者3年总生存率为93.2%,有盆腔淋巴结转移者为77.2%,差异有统计学意义,P=0.036。在外照射结束后接受腔内后装治疗和未接受后装治疗患者总生存率分别为96.6%和92.8%,盆腔控制率均为95.9%,差异无统计学意义,P值分别为0.183和0.519。结论:具有不良预后因素的宫颈癌患者接受术后放疗,可获得满意的总生存率、无瘤生存率和盆腔控制率,肿瘤远处转移为治疗失败主要原因。OBJECTIVE：To analyze the curative effects,complications and prognosis factors for cervical carcinoma patients with surgery and postoperative radiotherapy.METHODS：Totally 232 patients with stage ⅠA-ⅡB cervical cancer treated with surgery and postoperative radiotherapy had been collected for retrospective analysis.RESULTS： The 3-year overall survival rate,disease-free survival rate and local control rate for all patients were 92.5%,89.2%,93.3%,respectively.The 3 year overall survival rate for patients with or without pelvic lymph nodes were 77.2% and 93.2% with significantly statistic difference（P=0.036）.The 3 year overall survival for patients with or without intracavity brachytherapy were 96.6%,92.8% without significantly statistic difference,and the pelvic control rates were both 95.9%in these two group patients.CONCLUSION：The patients with cervical cancer who have infaust prognosis treated with surgery and postoperative radiotherapy can receive good local control and overall survival with acceptable side effects.Distant metastasis is main cause of death.

关 键 词：宫颈肿瘤 手术治疗 放射治疗 预后 

分 类 号：R737.33[医药卫生—肿瘤]