高沸醇有机木质素微粉制备及抗氧化性能  

Preparation and antioxidant capacity of high boiling solvent lignin nano-powder

作　　者：路祺[1] 朱明华[2] 祖元刚[1] 张莹[1] 张晓南[1] 李汶罡[1] 祖柏实[1] 张宝友[1] 

机构地区：[1]东北林业大学森林植物生态学教育部重点实验室 [2]东北林业大学生物质材料科学与技术教育部重点实验室

出　　处：《北京林业大学学报》2011年第5期69-74,共6页Journal of Beijing Forestry University

摘　　要：以制药生产提取的刺五加根茎剩余物作为原料,采用超临界反溶剂法(SAS)对高沸醇溶剂法所提取的木质素进行纳米化以及抗氧化活性检测实验。结果表明正交优化实验条件:沉淀反应釜温度35℃,沉淀反应釜压力30MPa,温度差+10℃,木质素溶液浓度0.5mg/mL。通过重复性验证实验,最终得到粒径(0.144±0.03)μm纳米级有机木质素。纳米和未纳米有机木质素DPPH自由基清除能力(EC50值)分别为(0.884±0.02)mg/mL、(0.563±0.02)mg/mL,表明纳米有机木质素DPPH自由基清除能力比未纳米有机木质素有大幅提高。Lignin was extracted from the Acanthopanax senticosus remainders,coming from pharmaceutical production process,with 1,4-butanediol as an extracting reagent.The supercritical antisolvent（SAS） process was studied to prepare nanoscale lignin and test its antioxidant capacity.The optimal condition by a four-level orthogonal design is as follows：precipitation temperature 35℃,precipitation pressure 30 MPa,temperature difference ＋10℃ and concentration of lignin solution 0.5 mg/mL.Nanoscale organic lignin with mean particle size of（0.144±0.03） μm was obtained by verification experiments.The EC50 of the nanoscale and non-nanoscale organic lignin on DPPH was（0.563±0.02） mg/mL and（0.884±0.02） mg/mL,respectively.The results indicated that the DPPH scavenging capacity of nanoscale organic lignin is more improved than that of non-nanoscale organic lignin.

关 键 词：超临界反溶剂法 纳米粉 有机木质素 抗氧化活性 BHA 

分 类 号：S781.42[农业科学—木材科学与技术]