5种海南岛药用植物抗肿瘤活性部位的筛选  

Antitumor Activities of Different Extracts from 5 Kinds of Medical Plants in Hainan

作　　者：王菁[1,2] 张园[1,2] 袁媛[2] 陈光英[2] 

机构地区：[1]海南师范大学生命科学学院,海南海口571158 [2]海南师范大学热带药用植物化学省部共建重点实验室,海南海口571158

出　　处：《海南师范大学学报（自然科学版）》2011年第3期301-306,共6页Journal of Hainan Normal University（Natural Science）

基　　金：教育部新世纪优秀人才支持计划项目(NCET-08-0656)

摘　　要：筛选猪屎豆、蒌叶、喜光花、广南天料木和红花天料木等5种药用植物的抗肿瘤有效部位.采用MTT法测试了该5种药用植物不同溶剂萃取物对四种癌细胞的体外抑制活性.证明了该5种药用植物的部分提取物对4种肿瘤细胞增殖有较强的抑制作用,量-效关系明显.The anti-tumor active extracts of 5 kinds of medicinal plants were screened, which are Crotalaria mucronata Desv, Piper betle L1, Actephila m errilliana, Homalium paniculiflorum and Homalium hainanensis. The MTT assay was used to test the antitumor activity of the different extracts of 5 kinds of medicinal plants against four kinds of cancer cells in vitro. Some of the extracts showed remarkable inhibitory activities against the four tumor cells, and expressed dose-effect relationship obviously.

关 键 词：药用植物 活性部位 抗肿瘤作用 MTT法 

分 类 号：R730.52[医药卫生—肿瘤]