血管内支架成形术治疗椎动脉起始段狭窄的疗效探讨  

Clinical Study of Stent-assistant Angioplasty for Treatment Stenosis of Vertebral Artery Origin

作　　者：严永兴 梁丽贞 陈涛 钟长扬 李鹏 

机构地区：[1]杭州市第三人医院,浙江杭州310009

出　　处：《心脑血管病防治》2011年第5期341-343,共3页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

基　　金：杭州市科技局科技计划资助项目(20090833B16)

摘　　要：椎动脉起始段狭窄或闭塞是后循环缺血性卒中的重要原因，常规的药物治疗对于椎动脉狭窄患者常不能获得持久疗效，预后较差[1．2]。近年来血管内支架成形术开始应用于脑血管病的治疗，它对于重建血管路径，增加脑血流量，Objective To study the efficacy, security and feasibility of stent-assistant angioplasty （SAA） in the treatment of vertebral artery origin stenosis. Methods The SAA was performed in 16 patients with symptomatic vertebral artery origin stenosis. Technical success rate, perioperative complication and long-term follow-up results were evaluated. Results 16 flexible balloon expandable stents were implanted in 16 patients. Technical success rate was 100%, and the average stenosis was reduced from （82.44±8.59）% to （4.19 ± 3.23）% （P 〈 0.01 ）. No serious complications happened in pcrioperative period. During the further clinical follow-up period from 3 months to 32 months（mean 20.8 months）, 2 patients had recurrence of symptoms, and the remaining patients had good effect and had no cerebral ischemic events. Of which 2 patients had in-stent restenosis . Conclusions SAA was a safe and effective method for treatment of senile vertebral artery stenosis.

关 键 词：血管内支架成形术 椎动脉狭窄 动脉起始段 药物治疗 疗效 缺血性卒中 脑血管病 血管路径 

分 类 号：R743.3[医药卫生—神经病学与精神病学]