99Tcm—MIBI显像对腮腺区肿块的诊断价值  

99TCm-MIBI SPECT for the differential diagnosis of parotid tumors

作　　者：刘洪伟[1] 李宁毅[2] 

机构地区：[1]山东省济宁市第一人民医院口腔颌面外科,272111 [2]青岛大学医学院附属医院口腔颌面外科

出　　处：《中华核医学杂志》2011年第5期310-312,共3页Chinese Journal of Nuclear Medicine

摘　　要：目的探讨99Tc^m_MIBI显像在腮腺肿块术前定性诊断中的价值。方法对32例单侧腮腺肿块患者术前行腮腺区99Te^m-MIBI显像，所有病例均行早期和延期显像以判断肿块性质。判断结果与病理诊断相比较。定性分析行Fisher确切概率法检验，组间病变侧与对侧放射性摄取比值（T／N）比较行t检验。结果99TcA^m．MIBI显像对腮腺区恶性肿瘤诊断的灵敏度、特异性和准确性分别为90．00％（9／10）、86．36％（19／22）和87．50％（28／32）。22例腮腺区良性肿块中显像阴性19例（86．36％），假阳性3例（13．64％）；10例腮腺恶性肿块中显像阳性9例（90．00％），假阴性1例（10．00％）；定性分析经Fisher确切概率法检验差异有统计学意义（P=0．00018）。腮腺区良恶性肿块T／N：早期相分别为1．45±0．38和1．65-t-O．63，两者差异有统计学意义（t=20．4，P〈0．01）；延期相分别为1．43±0．56和1．77-4-0．59，两者差异也有统计学意义（t=2．4，P〈0．05）。结论99Tc^m一MIBI显像可作为腮腺区肿块术前定性诊断的有效辅助手段。Objective To evaluate the clinical value of 99Tcm-MIBI SPECT for the differential diag- nosis of parotid tumors before treatment. Methods 99Tcm-MIBI SPECT imaging of the parotid region was obtained in 32 patients with parotid tumors before surgery. Early and delayed 99Tcm-MIBI imaging were per- formed in all patients and the diagnosis was confirmed by pathological results after surgery. The ratio of radi- oactivity between the tumor and opposite side of normal parotid tissue （T/N） was measured. Fisher exact probability test and t test were used for statistical analysis. Results The sensitivity, specificity and accura- cy of 99Tcm-MIBI SPECT imaging for the differential diagnosis of parotid tumor were 90.00% （9/10）, 86.36% （19/22） and 87.50% （28/32） , respectively. Among 22 patients who had benign tumors, 19 （86.36%） showed negative findings, and the other 3 （13.64%） patients showed false positive results. In l0 patients with malignant tumors, 1 （ 10.00% ） had false negative findings, and all the other 9（90.00% ） patients showed positive results. The difference between the benign and malignant groups was statistically significant （P = 0. 00018 ）. In the early images, the T/N ratios of benign and malignant parotid tumors were 1.45 ± 0.38 and 1.65 ± 0.63 （ t = 20.4, P 〈 0.01 ） , respectively ; and in the delayed images, the ratios were 1.43 ~0.56 and 1.77 ±0.59 （t =2.4, P〈0.05） , respectively. Conclusion 99Tem-MIBI SPECT imaging might be useful for the differential diagnosis of parotid tumors before surgery.

关 键 词：腮腺肿瘤 放射性核素显像 MIBI 

分 类 号：R739.8[医药卫生—肿瘤]