急性脑梗死与颈动脉粥样硬化及脂蛋白(a)的相关性研究  

The Relationship between Acute Cerebral Infarction and Carotid Atherosclerosis,Lipoprotein(a)

作　　者：谷万丹 曲松滨[2] 

机构地区：[1]哈尔滨市第四医院干部病房,黑龙江哈尔滨150026 [2]哈尔滨医科大学附属第一医院,黑龙江哈尔滨150001

出　　处：《黑龙江医学》2011年第10期727-730,共4页Heilongjiang Medical Journal

摘　　要：目的研究急性脑梗死与颈动脉粥样硬化及脂蛋白(a)之间的关系。方法选择急性脑梗死患者160例为病例组,均行血脂蛋白(a)以及颈部血管超声检查,与70例同期门诊体检者进行对照比较。结果病例组血脂蛋白(a)水平及颈动脉斑块积分均高于对照组(P<0.001)。急性脑梗死患者中,脂蛋白(a)水平分别为颈动脉内膜正常组15.61±15.47、颈动脉内膜增厚组19.95±7.66、颈动脉轻度狭窄组25.98±8.27、颈动脉中度狭窄组44.70±12.55、颈动脉重度狭窄-闭塞组62.18±13.36,两两比较差异均有显著性(P<0.05)。结论脂蛋白a增高、颈动脉粥样硬化均为脑梗死的危险因素,且急性脑梗死病人血脂蛋白a水平与动脉粥样硬化程度相关,对脑梗死的治疗及预防有重要意义。Objective To study the relationship between acute cerebral infarction and carotid atherosclerosis,lipoprotein（a）.Methods 160 cases with acute cerebral infarction were detected of LP（a） and carotid ultrasonography.The results were compared with the control group of 70 cases.Results The integral of carotid artery plaque and the level of LP（a） are higher than that of the control group（P0.001）.The LP（a） level in 5 groups of acute cerebral infarction were respectively（15.61±15.47）mg/L,（19.95±7.66） mg/L,（25.98±8.27）mg/L,（44.70±12.55）mg/L,（62.18±13.36）mg/L.It has significant difference to compare each other（P0.05）.Conclusion The increase of LP（a） and carotid atherosclerosis mightbe the risk factors of cerebral infarction.And the level of LP（a） has relationship with the degree of carotid atherosclerosis in acute cerebral infarction.It have important clinical significance to treat and prevent cerebral infarction.

关 键 词：脑梗死 颈动脉粥样硬化 脂蛋白A 

分 类 号：R743.3[医药卫生—神经病学与精神病学]