高-低氧放疗在子宫内膜癌中的应用及临床观察  

Clinical analysis of carbogen plus low concentration oxygen radiotherapy in patients with carcinoma of the endometrium

作　　者：沈雄虎[1] 孙红花[1] 黄京华[1] 韩龙海[1] 崔雄[1] 朴龙镇[1] 

机构地区：[1]吉林省延边大学附属医院肿瘤科,吉林延吉133000

出　　处：《中国现代医学杂志》2011年第18期2164-2165,2169,共3页China Journal of Modern Medicine

基　　金：国家自然科学基金(No:81060166/H1602)

摘　　要：目的探讨高-低氧放疗在子宫内膜癌姑息治疗中的价值。方法 80例晚期子宫内膜癌患者分为高-低氧放疗组和普通放疗组,每组40例,比较放疗后两组的副反应、生存质量和生存时间。结果放疗后高-低氧组的白细胞减少,较普通组轻(P<0.05),两组血红蛋白和血小板的减少无明显差异(P>0.05);生存质量及生存时间,高-低氧组优于普通组(P<0.05)。结论在子宫内膜癌的姑息治疗中,高-低氧放疗优于普通放疗。[ Objective ] To study the value of carbogen plus low concentration oxygen radio therapy （CPLCOR） in patients with carcinoma of the endometrium. [ Methods ] Eighty patients with advanced carcinoma of the endometrium were assigned to two groups equally at random. One group took up earbogen plus low concentration oxygen radiotherapy and the controller took up traditional radiotherapy （TR）.The side effects, survival and quality of life were compared. [ Results ] The degree of WBC descent in CPLCOR group was less than the control group （P 〈0.05） and there was no statistical difference in descent of HGB and PLT. The group that took up earbogen plus low concentration oxygen radiotherapy was superior to the controller on survival span and quality＇of life （P 〈0.05）. [ Conclusion ] In the palliative therapy of carcinoma of the endometrium, earhogen plus low concentration oxygen radiotherapy was superior to traditional radiotherapy.

关 键 词：放射治疗 高-低氧 子宫内膜癌 

分 类 号：R737.33[医药卫生—肿瘤] R815[医药卫生—临床医学]