不同器官浸润性微乳头状癌形态病理学及基础研究进展  

Progress in Pathomorphology and Basic Research of Invasive Micropapillary Carcinomas in Different Organs

作　　者：郝金燕[1] 杨壹羚[1] 李帅(综述)[1] 付丽(审校)[1] 

机构地区：[1]天津医科大学附属肿瘤医院乳腺病理科,乳腺癌防治教育部重点实验室,天津市300060

出　　处：《中国肿瘤临床》2011年第19期1230-1233,1238,共5页Chinese Journal of Clinical Oncology

基　　金：国家自然科学基金重点项目(编号:30930038);教育部长江学者乳腺癌创新团队奖励计划(编号:IRT0743);国家863重大项目(编号:2006AA02A249);国家973重大项目(编号L2009CB521700);天津市应用基础与前沿技术计划项目(编号:08JCZDJC23700)资助~~

摘　　要：浸润性微乳头状癌是一种少见的具有特殊形态学特征以及高淋巴结转移、高淋巴管浸润等预后不良生物学行为的恶性肿瘤。近年来研究发现其可以发生在不同的器官,包括乳腺、膀胱、肺、唾液腺、腮腺、结肠、胆管、胃和卵巢等,染色体异常在其发生、发展过程中发挥了重要作用。作者综述了各器官浸润性微乳头状癌的形态病理学及基础研究进展。Invasive micropapillary carcinoma is a rare malignant tumor with distinct pathomorphology and biological behaviorsexhibiting unfavorable prognoses, such as high-risk lymph node metastasis and high-degree lymphovascular invasion. Over the past few years, studies have found that this tumor can occur in various organs including the breast, urinary bladder, lung, salivary glands, colon, bile duct, stomach, and ovaries. Chromosomal aberration plays a key role in tumorigenesis and progression of a tumor. In the present article, progress in the pathomorphology and genetics of invasive micropapillary carcinomas in different organs was reviewed.

关 键 词：浸润性微乳头状癌 形态病理学 基础研究 

分 类 号：R737.9[医药卫生—肿瘤]